Results 131 to 140 of about 529,990 (264)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Разработка и регистрация лекарственных средств, 2019 The main objectives of stress experiments and tests corresponding to them, and also stress experiments for preparation of solutions for check of system suitability of chromatographic systems are in detail considered.
N. A. Epshtein
doaj
The Effect of Zirconium Incorporation on the Bronsted Acidity of Zeolite: A DFT Study
, 2011 The incorporation of zirconium atoms into the framework of some aluminosilicate molecular sieves can enhance the reactivities of some typical strong Bronsted acid needed reactions, and the strengthening of Bronsted acidity were regarded as one possible ...
Zheng, AM +2 more
core
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Defining “incorporation” with bare singulars in Romanian [PDF]
Bucharest Working Papers in Linguistics, 2014 This paper revisits the problem of bare singular count nouns in Romanian (see Tănase-Dogaru 2007, 2008). The vantage point bare singulars are analyzed from in this paper is the framework known in the literature as “incorporation”.
Mihaela Tănase-Dogaru
doaj
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
, 1936 Series 17893 | Washington County (Utah). County Clerk | Incorporation case files | CentralIncorporation Case Files contain at a minimum the original articles of incorporation and any subsequent amendments to corporations.
Washington County (Utah). County Clerk
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Neural Processing Letters 10: 231--242, 1999.
, 1999 The incorporation of prior knowledge into neural networks can improve neural network learning in several respects, for example, a faster learning speed and better generalization ...
Yaochu Jin +2 more
core