Results 111 to 120 of about 529,990 (264)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The article examines a topical scientific problem associated with a comprehensive reconstruction of educational practices that functioned in the Caucasus during the imperial period.
O. Shafranova, M. Trofimov
doaj
Field incorporation of straw and its effects on soil microbial biomass and soil inorganic N
The fumigation-extraction method was used to measure changes in soil microbial biomass in a field experiment following incorporation of 10 t ha−1 wheat straw, with and without 100 kg N ha−1 (as NH4NO3). into a silty clay loam soil in autumn 1987.
Ocio, J. A. +2 more
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
INTERMEDIATE PRECISION DETERMINATION AT VALIDATION OF METHODS IN PHARMACY
Merits and demerits of six ways of an assessment of an intermediate precision (IP) for validation of analytical methods are considered. It is established that only four of them can be recommended for IP assessment, and three - with restrictions ...
N. A. Epshtein
doaj
This article examines the original concept of the political history of Abkhazia in the first half of the XIX century which was reconstructed by means of qualitative analysis of a well-known narrative source - «Memories» by G. I. Philipson.
N. A. Trapsh
doaj
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Compound and Incorporation Constructionsas Combinations of Unexpandable Roots
This paper offers definitions of the terms compound construction, compoundand incorporation constructionthat can be applied to all languages in the same way.
Martin Haspelmath
doaj +1 more source
Laws and regulations of the Incorporation of Maltmen in Glasgow.
Mode of access ...
Glasgow (Scotland). Incorporation of Maltmen.
core

