Results 121 to 130 of about 529,990 (264)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

VALIDATION OF CHROMATOGRAPHIC METHODS: ROBUSTNESS INVESTIGATION WITH USE OF EXPERIMENTAL DESIGN

Разработка и регистрация лекарственных средств, 2019
This article covers the theoretical and practical basics of research of the robustness of chromatographic methods on the base of Plackett - Burman design.
N. A. Epshtein
doaj  

A common trajectory of gut microbiome development during the first month in healthy neonates with limited inter-individual environmental variations

Scientific Reports
The early development of the gut microbiome is governed by multiple factors and has significantly long-term effects on later-in-life health. To minimize inter-individual variations in the environment, we determined developmental trajectories of the gut ...
Xing-An Wang, Ju-Pi Li, Maw-Sheng Lee, Shun-Fa Yang, Yi-Sheng Chang, Ling Chen, Chang-Wei Li, Yu-Hua Chao   +7 more
doaj   +1 more source

Incorporation of heparin-binding proteins into preformed dextran sulfate-chitosan nanoparticles

, 2016
Paula Zaman,1 Julia Wang,1 Adam Blau,1 Weiping Wang,2 Tina Li,1 Daniel S Kohane,2 Joseph Loscalzo,1 Ying-Yi Zhang1 1Department of Medicine, Brigham and Women’s Hospital, 2Department of Anesthesiology, Boston Children’s Hospital, Harvard ...
Blau A, Zhang YY, Kohane DS, Li T, Zaman P, Loscalzo J, Wang W, Wang J   +7 more
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Maeser

, 1936
Series 5015 | Uintah County (Utah). County Clerk | Incorporation case files | MaeserIncorporation Case Files contain at a minimum the original articles of incorporation and any subsequent amendments to corporations. Articles of incorporation constitute a
Uintah County (Utah). County Clerk
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Does repeated biochar incorporation induce further soil priming effect?

, 2017
Purpose Positive priming effect following the incorporation of biochar may partially reduce the biochar-induced soil carbon (C) sequestration. We hypothesize that repeated biochar incorporations induce further priming effect in the soil that was already ...
Kuzyakov, Y., Qimei Lin, Lin, Qimei, Mark Durenkamp, Kuzyakov, Yakov, Durenkamp, Mark, Lin, Q. M., Luo, Yu, Durenkamp, M., Yakov Kuzyakov, Yu Luo, Luo, Y.   +11 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Hurricane

, 1912
Series 17893 | Washington County (Utah). County Clerk | Incorporation case files | HurricaneIncorporation Case Files contain at a minimum the original articles of incorporation and any subsequent amendments to corporations.
Washington County (Utah). County Clerk
core