Results 81 to 90 of about 1,204,472 (329)
Current Therapeutic Research, 2020 : Background: Coronavirus disease 2019 (COVID-19) has currently become a major global public health problem. The prevalence of COVID-19 has increased rapidly worldwide.
Gizachew Tadesse Wassie, MPH +4 more
doaj +1 more source
PENGARUH LAMA INKUBASI TERHADAP PERTUMBUHAN KUMAN PADA KULTUR DARAH PENDERITA SEPTIKEMIA DI RSUP DR. KARIADI SEMARANG PERIODE JANUARI - APRIL 2008 [PDF]
, 2008 Backgrounds: Septicemia is a dangerous systemic bacterial infection which has a high mortality rate. Immediate diagnosis empirical therapy of antibiotic plays important role on the patient prognosis.
Azasiyasa, Hakka
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Association between Severity of MERS-CoV Infection and Incubation Period
Emerging Infectious Diseases, 2016 We analyzed data for 170 patients in South Korea who had laboratory-confirmed infection with Middle East respiratory syndrome coronavirus. A longer incubation period was associated with a reduction in the risk for death (adjusted odds ratio/1-day ...
Victor Virlogeux +3 more
doaj +1 more source
Cocoon viability and evidence for delayed hatching by the earthworm Lumbricus terrestris in a laboratory-based study. [PDF]
, 2014 Clitellate Lumbricus terrestris, obtained from 5 commercial suppliers (A-E) and also field collected (F) - grassland in Preston, Lancashire, UK, were kept under controlled environmental conditions (15 °C and 24 h darkness) in a sterilised loam soil and ...
Butt, Kevin Richard +1 more
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Time-Dependent Effects of Stress on Cocaine Conditioned Place Preference Using a Rat Model of Posttraumatic Stress Disorder [PDF]
, 2011 Posttraumatic Stress Disorder (PTSD) affects approximately 8% of the entire population within their lifetimes. A startling trend of co-occurring PTSD and cocaine use has surfaced among humans who express these disorders.
Helpenstell, Lily K.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Reproductive capacity of the red cusk-eel genypterus chilensis (Guichenot, 1848) in captivity [PDF]
, 2018 Indexación: Scopus.This work was supported by the FONDEF Project D06I 1024 “Development of technologies for the production of red cusk-eel fingerlings (Genypterus chilensis)”.Genypterus chilensis is a marine fish of high gastronomic demand, whose capture
Barnert, M. +7 more
core +1 more source