Results 91 to 100 of about 2,182,704 (297)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Changes in dominant Escherichia coli and antimicrobial resistance after 24 hr in fecal matter. [PDF]
, 2018 Intestinal bacteria carry antimicrobial resistance (AMR) genes in mobile genetic elements which have the potential to spread to bacteria in other animal hosts including humans.
Barrera, Sofía +3 more
core +2 more sources
Asian Journal of Transfusion ScienceBACKGROUND AND OBJECTIVES: Collection and providing standard blood samples for examination is critical for all medical laboratories. Currently, for all blood samples taken from the elderly and young people, the same preparation protocol is applied.
Mahsa Yazdanbakhsh +4 more
doaj +1 more source
Investigation of Growth Kinetics of Fe2B Layers on AISI 1518 Steel by the Integral Method
High Temperature Materials and Processes, 2019 The AISI 1518 steel was pack-borided in the temperature range 1123–1273 K for a treatment ranging from 2 to 8 h. A compact single boride layer (Fe2B) was formed at the surface of the AISI 1518 steel using the mixture of powders composed of 20 % B4C, 10 %
Elias-Espinosa M. +6 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Performance of three commercial lipases in a model enzyme modified cheese system : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Food Technology at Massey University [PDF]
, 1999 The effects of Amano 'R' (from Penicillium roqueforti), Palatase (from Mucor miehei) and kid lipase (from kid goat) activity on hydrolysis of triglycerides in a constant enzyme modified cheese (EMC) base have been investigated.
Gunaratne, Jagath Thusitha Kumara
core
Jurnal Teknologi & Industri Hasil Pertanian, 2018 This study aimed to obtain N-Amino and Total Soluble Solids (TSS) in the extract earthworms. The material used is earthworm type Lumbricus rubellus with age about 40 days.
Nur Hidayat +2 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source