Results 51 to 60 of about 2,752 (194)

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +206 more
wiley   +1 more source

Factors Associated with Indacaterol Response in Tuberculosis-Destroyed Lung with Airflow Limitation

open access: yesTuberculosis and Respiratory Diseases, 2019
Background Pulmonary tuberculosis can result in anatomical sequelae, and cause airflow limitation. However, there are no treatment guidelines for patients with a tuberculosis-destroyed lung.
Tae Hoon Kim, M.D., Ph.D.   +2 more
doaj  

Budget impact model of indacaterol/glycopyrronium in the treatment of chronic obstructive pulmonary disease in Italy based on the FLAME study

open access: yesGlobal & Regional Health Technology Assessment, 2018
Purpose: We aimed to estimate the 3-year budget impact of replacing salmeterol/fluticasone with indacaterol/glycopyrronium for the treatment of chronic obstructive pulmonary disease patients in Italy.
Andrea Aiello   +2 more
doaj   +1 more source

Cardio- and cerebrovascular safety of indacaterol vs formoterol, salmeterol, tiotropium and placebo in COPD [PDF]

open access: yes, 2011
SummaryPurposeAs COPD patients commonly suffer cardio- and cerebrovascular (CCV) co-morbidities, our purpose was to establish the CCV safety profile of indacaterol, a novel, inhaled, long-acting β2-agonist for COPD.MethodsThe indacaterol clinical trial ...
Chung, Kian Fan   +9 more
core   +1 more source

Clinical Application Guideline of Combination With Traditional Chinese Medicine and Western Medicine in the Prevention and Treatment of Chronic Obstructive Pulmonary Disease (2024)

open access: yesJournal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Aim Chronic Obstructive Pulmonary Disease (COPD) is a common chronic airway disease that can lead to decreased lung function in patients. It places a heavy economic burden on patients and society. Traditional Chinese medicine (TCM) and Western medicine have played important roles in managing COPD.
Di Wu   +17 more
wiley   +1 more source

Indacaterol for chronic obstructive pulmonary disease: systematic review and meta-analysis.

open access: yesPLoS ONE, 2013
BackgroundInhaled bronchodilators are the first-line therapy for COPD. Indacaterol is a novel addition to existing long-acting bronchodilators.ObjectivesSystematic review of randomized controlled trials (RCT) ON efficacy and safety of indacaterol as ...
Vincent C H Chung   +4 more
doaj   +1 more source

Identification of Clinically Approved Drugs Indacaterol and Canagliflozin for Repurposing to Treat Epidermal Growth Factor Tyrosine Kinase Inhibitor-Resistant Lung Cancer

open access: yesFrontiers in Oncology, 2017
In advanced lung cancer, epidermal growth factor tyrosine kinase inhibitors (EGFR TKIs) have extraordinary clinical efficacy. However, their usefulness is severely compromised by drug resistance mediated by various mechanisms, the most important of which
Hongjian Li   +7 more
doaj   +1 more source

Dehydrogenative Coupling Reaction for the Synthesis of 5‐ and 6‐Heterocyclic Derivatives Catalyzed by Earth‐Abundant Metal‐Based Complexes

open access: yesAsian Journal of Organic Chemistry, Volume 14, Issue 5, May 2025.
Quinolin‐2(1H)‐one, a nitrogen‐containing heterocycle, is central to medicinal and synthetic chemistry, featured in bioactive compounds like Brexpiprazole and Indacaterol. Advances in synthesis are reviewed here, including metal‐catalyzed and photoinduced strategies, enhance efficiency and selectivity. Innovations like borrowing hydrogen methods enable
Nicolas Joly   +4 more
wiley   +1 more source

Implication of Central β2 Adrenergic Receptor for the Development of Novel Drugs Against Alzheimer's Disease

open access: yesArchiv der Pharmazie, Volume 358, Issue 4, April 2025.
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a progressive onset of symptoms, including memory loss, accompanied by other neurological impairments. This progression is attributed to the deterioration of neuronal connections and a decrease in neurotransmission.
Alice Wang   +3 more
wiley   +1 more source

Expert opinion on gray areas in asthma management: A lesson from the innovative project “revolution in asthma” of the Italian thoracic society (AIPO‐ITS)

open access: yesClinical and Translational Allergy, Volume 15, Issue 2, February 2025.
Abstract Background Despite the availability of numerous guidelines for asthma management, their recommendations are not consistently implemented in clinical practice. This discrepancy between guidelines and real‐world practice among Italian healthcare professionals was explored during the “Revolution in Asthma” training program, which identified “gray
Adriano Vaghi   +17 more
wiley   +1 more source

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