Results 31 to 40 of about 5,146 (174)

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Combination of perindopril/indapamide in secondary prevention of stroke and other vascular events: A combined analysis of ADVANCE, PROGRESS and HYVET trials

Bangladesh Journal of Pharmacology, 2011
Perindopril/indapamide combination has been shown to reduce cardiovascular risk in different groups of patients. A total of 18,529 patients (9,272 receiving perindopril/indapamide and 9,257 receiving placebo) were included in this meta-analysis involving
Sougat Sourendra Sarkar
doaj   +1 more source

Optimal Organ Protection and Blood Pressure Control with the Single Pill Combination Lisinopril, Amlodipine and Indapamide in Arterial Hypertension

Рациональная фармакотерапия в кардиологии, 2020
Aim. To evaluate the single pill combination with lisinopril, amlodipine and indapamide ability in additional angioprotection achievement in patients with arterial hypertension and high pulse wave velocity (PWV) regardless on previous antihypertensive ...
S. V. Nedogoda, T. N. Sanina, V. V. Tsoma, A. A. Ledyaeva, E. V. Chumachek, A. S. Salasyuk, D. S. Vlasov, O. I. Bychkova   +7 more
doaj   +1 more source

Effective therapy of hypertension from the standpoint of patient-centered medicine

Кардиоваскулярная терапия и профилактика, 2023
The article presents current data on the choice of antihypertensives from the standpoint of patient-centered medicine. The advantages of combined initial therapy includes high medical adherence, achievement of target blood pressure, and organ protection.
V. I. Podzolkov, M. V. Vetluzhskaya, A. E. Bragina, A. A. Abramova, I. Zh. Loriya, I. D. Medvedev, D. V. Akvitskaya   +6 more
doaj   +1 more source

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale

Geriatrics &Gerontology International, Volume 26, Issue 1, January 2026.
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi, Shuang Liu, Yasuyuki Suzuki, Yuuka Shibata, Shizuo Yamada   +4 more
wiley   +1 more source

Development of structure and methods of standardization of capsules indapamide

RUDN Journal of Medicine, 2008
There are established optimum parameters of technological process of reception and structure capsule weights indapamide. Normative parameters of quality of capsules indapamide 2,5 mg are proved.
A B Mashutin, E V Blynskaja, S N Suslina, K V Alexeev   +3 more
doaj  

A Validated RP-HPLC Method for Simultaneous Estimation of Atenolol and Indapamide in Pharmaceutical Formulations

E-Journal of Chemistry, 2011
A simple, fast, precise, selective and accurate RP-HPLC method was developed and validated for the simultaneous determination of atenolol and indapamide from bulk and formulations.
G. Tulja Rani, D. Gowri Sankar, P. Kadgapathi, B. Satyanarayana   +3 more
doaj   +1 more source

Successful Clozapine Rechallenge in a 40‐Year‐Old Male Patient With Paranoid Schizophrenia After Clozapine‐Associated Myocarditis

Case Reports in Psychiatry, Volume 2026, Issue 1, 2026.
Background Clozapine‐associated myocarditis (CAM) is the most common inflammatory adverse effect under clozapine treatment. In the absence of equally effective therapeutic alternatives for treating treatment‐resistant schizophrenia (TRS), clinicians are often faced with the question of whether to rechallenge clozapine in patients who have experienced ...
Lukas Zabel, Nathalie Ersek, Andreas B. Hofmann, Lena Machetanz, Johannes Kirchebner, Susanne Stübner, Philipp Sand   +6 more
wiley   +1 more source

ORIGINAL Programme: study background and design

Кардиоваскулярная терапия и профилактика, 2010
The paper presents the design of the ORIGINAL Programme (substituting indapamide generics with arifon retard in patients with arterial hypertension), evaluating blood pressure (BP) reduction in arterial hypertension (AH) patients starting the treatment ...
Yu. A. Karpov
doaj  

Clinical use of a fixed-dose combination of telmisartan and indapamide in hypertension. Expert Council resolution

Российский кардиологический журнал
The aim of the expert council "First star duo of telmisartan and indapamide in the Russian Federation", dedicated to the introduction of a new fixed-dose combination of telmisartan and indapamide (modified-release tablets) into clinical practice was to ...
A. O. Konradi, F. T. Ageyev, A. S. Galyavich, Yu. A. Karpov, Zh. D. Kobalava, Yu. V. Kotovskaya, S. V. Nedogoda, A. O. Nedoshivin, O. N. Tkacheva   +8 more
doaj   +1 more source