Results 91 to 100 of about 2,486,152 (319)
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Data archiving for dissemination within a Gulf nation
IASSIST Quarterly, 2019 Since 2008, Qatar University’s Social and Economic Survey Research Institute (SESRI), has been collecting nationally representative survey data on social and economic issues.
Brian Washington Mandikiana +2 more
doaj +1 more source
Determinantal Processes and Independence
, 2006 We give a probabilistic introduction to determinantal and permanental point processes. Determinantal processes arise in physics (fermions, eigenvalues of random matrices) and in combinatorics (nonintersecting paths, random spanning trees).
Hough, J. Ben +3 more
core +2 more sources
On Independence Domination [PDF]
, 2013 Let G be a graph. The independence-domination number is the maximum over all independent sets I in G of the minimal number of vertices needed to dominate I. In this paper we investigate the computational complexity of independence domination for graphs in several graph classes related to cographs. We present an exact exponential algorithm.
Hsiang-Hsuan Liu +4 more
openaire +3 more sources
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
BRITISH AND NIGERIA’S UNDERDEVELOPMENT: REVISIT ANALYSIS
International Studies JournalThis paper examines the concept of imperialism which has been implicated in the underdevelopment of Nigeria like other African Countries where it had been at work While they had long operated in Nigeria, new Imperialism that relates to colonialism is ...
INDEPENDENCE C. ENYINDAH +1 more
doaj
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Independence in constraint logic programs
, 1993 Studying independence of literals, variables, and substitutions has proven very useful in the context of logic programming (LP). Here we study independence in the broader context of constraint logic programming (CLP).
García de la Banda, M. +2 more
core +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
FEBS Letters, EarlyView.TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source