Results 81 to 90 of about 948,462 (255)

Association of Urinary Equol Concentration with Frailty in Community-Dwelling Older Adults: The Itabashi Longitudinal Study on Aging

open access: yesClinical Interventions in Aging
Narumi Kojima,1 Takashi Shida,1 Takahisa Ohta,1 Keiko Motokawa,2 Tsuyoshi Okamura,3 Hirohiko Hirano,2 Hiroyuki Sasai1 1Frailty and Musculoskeletal Health Research, Research Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute ...
Kojima N   +6 more
doaj  

Assessing the influence of fiscal and monetary policies on carbon dioxide emissions

open access: yesLatin American Journal of Central Banking
This paper examines the impact of fiscal and monetary policies on carbon dioxide emissions in Trinidad and Tobago, using data from 1970 to 2020. We use a fiscal policy index based on government revenue and expenditure, a monetary policy index based on ...
Avinash Ramlogan, Andell Nelson
doaj   +1 more source

Data archiving for dissemination within a Gulf nation

open access: yesIASSIST Quarterly, 2019
Since 2008, Qatar University’s Social and Economic Survey Research Institute (SESRI), has been collecting nationally representative survey data on social and economic issues.
Brian Washington Mandikiana   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Effects of engaging in remunerated productive activities on people with cognitive impairment: a pilot study

open access: yesBMC Research Notes
Objective Approximately 40% of older adults in Japan express a desire to continue working for as long as possible. In interviews conducted by the authors with members of an inclusive workplace that accommodates individuals regardless of age or background,
Hana Sakurai   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Independence [PDF]

open access: yes, 2008
Operated by Augustus Hemenway of Boston, Independence managed to have the normal kind of accidents reported in the marine news of the day. Independence seems to have been an ordinary ship, neither setting records, nor causing commotion—at least until ...

core  

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