Results 171 to 180 of about 580 (262)

Prerequisites for entry to advanced nurse practitioner studies- a qualitative study of Norwegian nurse anesthetist students' experiences. [PDF]

BMC Med Educ
Aanderud-Larsen C, Østlien S, Leonardsen AL.   +2 more
europepmc   +1 more source

T Cell‐Independent Role of PD‐L1 in Kidney Repair: Mitigation of Tubular DNA Damage via PD‐L1/BRCA1 Interaction Following AKI

Advanced Science, EarlyView.
PD‐L1 is primarily expressed in renal tubules and upregulated in both murine models of AKI and renal biopsy samples from patients with AKI. PD‐L1 can promote adaptive TECs repair through interacting with BRCA1, independent of its canonical immunomodulatory function of T cells, and PD‐L1 supplementation may represent a promising therapeutic strategy for
Wei Jiang, Tao‐Tao Tang, Wei‐Jie Ni, Jin‐Xuan Wei, Liang‐Yun‐Zi Jiang, Qing Yin, Yi‐Lin Zhang, Zuo‐Lin Li, Yi Wen, Xin‐Lu Wang, Jun‐Yuan Shen, Xiao‐Jun Ouyang, Ming‐Zhu Zheng, Jian Xu, Xiaofei An, Lin‐Li Lv, Bi‐Cheng Liu, Bin Wang   +17 more
wiley   +1 more source

Using intersectional gender analysis to identify challenges in tuberculosis care at four health care facilities in Uganda. [PDF]

Infect Dis Poverty
Muttamba W, Omongot S, Najjingo I, Nuwarinda R, Buregyeya E, Del Barrio MO, Morgan R, Kirenga B, Ssali S.   +8 more
europepmc   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

KNTC1 introduces segmental heterogeneity to mitochondria. [PDF]

Dis Model Mech
Tsukamura A, Ariyama H, Hayashi N, Miyatake S, Okado S, Sultana S, Terakado I, Yamamoto T, Yamanaka S, Fujii S, Hamanoue H, Asano R, Mizushima T, Matsumoto N, Maruo Y, Mori M.   +15 more
europepmc   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Mendelian randomization study of sleep traits and risk of colorectal cancer. [PDF]

Sci Rep
Dimopoulou O, Fuller H, Richmond RC, Bouras E, Hayes B, Dimou N, Murphy N, Brenner H, Gsur A, Le Marchand L, Moreno V, Pai RK, Phipps AI, Um CY, van Duijnhoven FJB, Vodicka P, Martin RM, Platz EA, Gunter MJ, Peters U, Lewis SJ, Cao Y, Tsilidis KK.   +22 more
europepmc   +1 more source

Estimated need for anthelminthic medicines to control soil-transmitted helminthiases in school-aged children, 2020-2030. [PDF]

Infect Dis Poverty, 2020
Marocco C, Tediosi F, Bangert M, Mupfasoni D, Montresor A.   +4 more
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

A Systematic Bibliometric Review Analysis of Research on the Use of Waste Rubber Tyres in Building and Construction Materials and Their Applications. [PDF]

Polymers (Basel)
Castillo R, Alva A, París-Viviana O, Bosch M.   +3 more
europepmc   +1 more source