Results 61 to 70 of about 726,853 (265)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Four distinct models of learning health systems: Strength through diversity

Learning Health Systems
The concept of a learning health system (LHS) was established nearly 20 years ago as a unifying commitment to speed the generation and use of evidence primarily by leveraging rapid advances in data and technologies, resulting in optimized care for each ...
Charles P. Friedman, Sarah M. Greene
doaj   +1 more source

Understanding the Complexities : An Exploration of Internal and External Factors Affecting Student Accounting Learning Difficulties

Jurnal Paedagogy
This study examines factors influencing accounting learning difficulties among 138 students of the Accounting Education Program at Universitas Negeri Medan, with a sample of 117, which was determined using Slovin's formula and purposive sampling.
Tuti Sriwedari, Ulfa Nurhayani, Choms Gary Ganda Tua Sibarani, Haryani Pratiwi Sitompul, Weny Nurwendari   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Book Review of Athena Unbound: Why and How Scholarly Knowledge Should be Free for All

Open Praxis
Athena Unbound: Why and How Scholarly Knowledge Should be Free for All, by Peter Baldwin, Cambridge, MA, MIT Press, 2023, 360 pp., US$35.00 (hardcover), also available as open access eBook https://doi.org/10.7551/mitpress/14887.001.0001, ISBN 978-0-2620-
David Chun Yin Li
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Navigating education and parenthood: Teenage mothers' support systems in Namibia's Omusati region [PDF]

Journal of Studies in Social Sciences and Humanities
This research explored the experiences of teenage mothers enrolled in schools in the Omusati region of Namibia. The study examines how they perceive and navigate the support systems available to them in their ecological context.
Dr. Rauha Haipinge, Dr. Halima Namakula*
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

On the Independence Assumption in Neurosymbolic Learning

CoRR
Accepted at ICML ...
Emile van Krieken, Pasquale Minervini, Edoardo M. Ponti, Antonio Vergari   +3 more
openaire   +4 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source