Results 11 to 20 of about 1,619 (168)

NTRK1-rearranged histiocytosis: clinicopathologic and molecular features. [PDF]

Blood Adv
Non-Langerhans cell histiocytoses are a diverse group of histiocytic diseases. Different entities are defined based on clinical, histopathologic, and/or molecular characteristics. This study aimed to define NTRK-rearranged histiocytosis.
Fragneau R, Fraitag S, Kemps PG, Hélias-Rodzewicz Z, Roy S, Bonsang B, Bartlett AL, Dhar S, Jankofsky M, Zlocha J, Svojgr K, Krsková L, de Vries ACH, Verdijk RM, van Laar JAM, Leguit RJ, Drabent P, Carlsen ED, Ho J, Karunamurthy AD, Santi M, Jullié ML, Babor F, Lorsbach R, van Halteren AGS, Héritier S, Diamond EL, Durham BH, Kumar AR, Bhattacharya A, Haroche J, Donadieu J, Borkhardt A, Picarsic JL, Emile JF.   +34 more
europepmc   +3 more sources

Indeterminate Cell Histiocytosis: Report of a Case

Acta Medica Iranica, 2014
Indeterminate cell histiocytosis is a very rare disorder of histiocytes proliferation. It has both Langerhans and non-Langerhans cell histiocytosis immunophenotypic features.
Alireza Ghanadan, Kambiz Kamyab, Mazaher Ramezani, Azadeh Goodarzi, Maryam Daneshpajouh, Kamran Balighi, Mahsa Ansari, Seyyed Farzad Mirfallah Nassiri, Soroush Daklan   +8 more
doaj   +1 more source

Indeterminate Cell Histiocytosis Presenting with Leonine Facies

Acta Dermato-Venereologica, 2018
Cheng Chen, Giang Huong Nguyen, Yue-Ping Zeng   +2 more
doaj   +4 more sources

Erdheim-Chester disease associated with myeloid neoplasm: Clinical features, molecular landscape, and treatment outcomes. [PDF]

Hemasphere
Abstract Erdheim‐Chester disease (ECD) is frequently associated with clonal hematopoiesis and myeloid neoplasms (MN), but clinical phenotype and response to kinase inhibitors (KI) in this setting remain unclear. We analyzed 67 patients with ECD associated with MN (ECD‐MN) from a French national cohort and assessed ECD treatment response, MN progression,
Le Pogam A, Papo M, Hirsch P, Cohen-Aubart F, Emile JF, Delhommeau F, Duffau P, Razanamahery J, Nguyen-Khac F, Nunes Gomes C, Triboulet F, de La Rochefoucauld J, McAvoy C, Lazaro E, Hage-Sleiman M, Roos-Weil D, Chasset F, Jachiet V, Mekinian A, Fain O, Amoura Z, Hadjadj J, Haroche J.   +22 more
europepmc   +2 more sources

Recurrent ETV3::NCOA2 fusions and MAPK pathway mutations in indeterminate dendritic cell histiocytosis. [PDF]

Blood Adv
Kemps PG, Woei-A-Jin FJSH, Quint KD, van den Bos C, Naeije L, van Laar JAM, Vanden Bempt I, Koudijs MJ, Vorderman RHP, Stelloo E, Swennenhuis JF, Bruggink AH, Hebeda KM, Scheijde-Vermeulen MA, Diercks GFH, Verdijk RM, Jansen PM, Hauben E, Tousseyn T, Cleven AHG, van Wezel T, van Halteren AGS, Hogendoorn PCW.   +22 more
europepmc   +4 more sources

WHO classification of skin tumours: key updates in the fifth edition. [PDF]

Histopathology
This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Goldman-Lévy G, Barnhill R, Bastian BC, Kempf W, Elder D, Gerami P, Grayson W, Kazakov D, Massi D, Messina J, de la Fouchardière A, Lazar AJ, Brenn T, Rous B, Field A, Gill A, Hodge JC, Khoury JD, Leite K, Sayed S, Tan PH, Elenitsas R, Calonje E, Duncan LM, Zhiyong L, Moch H, Singh R, Wijesinghe H, Cree I, Lokuhetty D.   +29 more
europepmc   +2 more sources

Indeterminate dendritic cell tumor (IDCT) [PDF]

Vestnik Dermatologii i Venerologii, 2023
Indeterminate dendritic cell tumor (IDCT) is rare histiocytic tumor characterized by the proliferation of indeterminate dendritic cells. It is more often diagnosed in middle-aged people, in approximately equal proportions in men and women.
Evgenia V. Okladnikova, Vladimir M. Merk, Yuriy А. Krivopalov, Vladimir А. Khorzhevskii, Tatiana G. Ruksha   +4 more
doaj   +1 more source

Tissue-Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts. [PDF]

Am J Hematol
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Valent P, Wojta J, Kovanen PT, Hermine O, Fend F, Sotlar K, Greinix H, Geissler K, Hartmann K, Schwaab J, Herling M, Boccuni L, Kazianka L, John MV, Sperr WR, Zierfuss C, Tzankov A, Sillaber C, Minkov M, Hoermann G, Collin M, Horny HP, Haferlach T, Sibilia M, Haroche J, La Rosée P, Orfao A, Arock M.   +27 more
europepmc   +2 more sources

Intermediate-dose cytarabine is an effective therapy for adults with non-Langerhans cell histiocytosis

Orphanet Journal of Rare Diseases, 2022
Background Non-Langerhans cell histiocytosis, including Erdheim–Chester disease (ECD), Rosai–Dorfman disease (RDD), indeterminate cell histiocytosis (ICH), and unclassified histiocytosis, is a rare disorder lacking a standard treatment strategy.
Ting Liu, Hua-cong Cai, Hao Cai, Miao Chen, Wei Zhang, Jian Li, Dao-bin Zhou, Xin-xin Cao   +7 more
doaj   +1 more source

CD1a-positive dendritic cell-enriched pigmented purpuric dermatosis in association with dyslipidemia

Journal of Dermatology and Dermatologic Surgery, 2022
Indeterminate cells (ICs) are dendritic cells (DCs) that share the histologic features of Langerhans cells and macrophages but lack Birbeck granules. It remains unclear whether IC histiocytosis is a separate disease entity or a reactive process.
Tiffany Hinojosa, Daniel J Lewis, Madeleine Duvic, Carlos A Torres-Cabala   +3 more
doaj   +1 more source