Results 121 to 130 of about 12,784,680 (324)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Eccentric connectivity index [PDF]

, 2010
The eccentric connectivity index $\xi^c$ is a novel distance--based molecular structure descriptor that was recently used for mathematical modeling of biological activities of diverse nature. It is defined as $\xi^c (G) = \sum_{v \in V (G)} deg (v) \cdot
Ilić, Aleksandar
core  

Role of Low Ankle–Brachial Index in Cardiovascular and Mortality Risk Compared with Major Risk Conditions [PDF]

, 2019
Lia Alves‐Cabratosa, Maria García-Gil, Marc Comas‐Cufí, Jordi Blanch, Anna Ponjoan, Ruth Martí‐Lluch, Marc Elosua-Bayés, Dídac Parramon, Lourdes Camós, Rafel Ramos   +9 more
openalex   +1 more source

Correlation of triglyceride–glucose index and dyslipidaemia with premature coronary heart diseases and multivessel disease: a cross-sectional study in Tianjin, China [PDF]

, 2022
Ao Wei, Jingjing Liu, Le Wang, Senshuang Zheng, Hongliang Cong   +4 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

A two-stage retrieval-augmented generation framework for producing sustainable product design guidelines

Sustainable Futures
Design is fundamental to product development and is widely recognised as a key driver for supporting the transition to a circular economy. As a problem-solving process, design relies heavily on knowledge retrieval and generation.
Pingfei Jiang, Ji Han, Saeema Ahmed-Kristensen   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Index/Index [PDF]

Index on Censorship, 1982
openaire   +1 more source

Optimizing ensembles machine learning, genetic algorithms, and multivariate modeling for enhanced prediction of maize yield and stress tolerance index [PDF]

Muhammad Azrai, Muhammad Aqil, Nining Nurini Andayani, Roy Efendi, Suarni, Suwardi Suwardi, Muhammad Jihad, Bunyamin Zainuddin, Salim Salim, Bahtiar Bahtiar, Ahmad Muliadi, Muhammad Yasin, Muhammad Fitrah Irawan Hannan, Rahman, Amiruddin Syam   +14 more
openalex   +1 more source

Drought Monitoring from Fengyun Satellite Series: A Comparative Analysis with Meteorological-Drought Composite Index (MCI) [PDF]

, 2023
Aiqing Feng, Lulu Liu, Guofu Wang, Jian Tang, Xuejun Zhang, Yixiao Chen, Xijing He, Ping Liu   +7 more
openalex   +1 more source