Results 231 to 240 of about 6,276,135 (290)

Author Correction: The construction of a physical literacy assessment index system for junior high school students: a Chinese study. [PDF]

Sci Rep
Gao M, Che W, Qi S.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

The construction of the index system for nurses' innovation competence evaluation in China: A Delphi study. [PDF]

Heliyon
Ma LL, Zhang YJ, Rong S, Yao JX, Zhuang HR, Zhang WY.   +5 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Constructing a Resilience Assessment Index System for Tuberculosis Healthcare Services Under Public Health Emergencies: A Modified Delphi Study. [PDF]

Risk Manag Healthc Policy
Fan M, Liu Y, Liu K, Zhang C, Li Y, Liu X, Zhang H, Cheng J.   +7 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

[Development of a surface electromyography index system for orofacial muscles and validation of a discriminant model in unilateral molar occlusal interference]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Li W, Shen Y, Yang Y, Shan S, Gao Z, Wen A, Shang X, Tian Y, Guo S, Wang Y, Wang Y, Zhao Y.   +11 more
europepmc   +1 more source

Construction of a sensitive index system for nursing quality in the perioperative period of liver transplantation based on the Three-Dimensional Quality Structure theory. [PDF]

BMC Health Serv Res
Wang B, Sun W, Liu F, Zheng T, Quan L, Liu G, Lin H, Qiao Y, Cai J, Huang X.   +9 more
europepmc   +1 more source