Results 71 to 80 of about 10,852 (301)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Does Fundamental Indexation Lead to Better Risk Adjusted Returns? New Evidence from Australian Securities Exchange [PDF]
Fundamental indexing based on accounting valuation has drawn significant interest from academics and practitioners in recent times as an alternative to capitalization weighted indexing based on market valuation.
Anup Basu, Brigette Forbes
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Journal of the Linnean Society of London, Zoology, 1915 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +1 more source
Real Wages and the Terms of Trade: Alternative Indexation Rules for an Open Economy [PDF]
This paper examines the desirability of wage indexation in an open economy subject to economic disturbances which change the terms of trade and raise the prices of imported goods. Two indexation rules are considered, the traditional form of indexation to
Richard C. Marston
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
THE RELATIONSHIP BETWEEN EFFICIENCY WAGES AND PRICE INDEXATION IN A NOMINAL WAGE CONTRACTING MODEL [PDF]
This paper examines how a link between efficiency wages and price indexation can arise in a simple nominal wage contracting model. We show that, the more elastic the worker¡¯s effort is with respect to real wages, the looser the optimal linkage of ...
Shik Heo
core
Moneta e Credito, 2014 In a recent paper F. Modigliani and T. Padoa-Schioppa analyzed the characteristics of an economy, such as Italy’s, in which wages are 100% protected against inflation through the mechanism of wage indexation to prices.
P.C. PADOAN, M.L. PETIT
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source