Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Indication and Technical Application of Stripping
Interproximal enamel reduction is a technique used for creating space in cases of mild or moderate crowding. There are several indications and contraindications determined by the tooth shape and the percentage of the caries index.
Georgiadis A.A. +3 more
doaj +1 more source
Will Geographical Indications Supply Excessive Quality? [PDF]
Consumer/Household Economics, Marketing,
Merel, Pierre R., Sexton, Richard J.
core +1 more source
Corporate governance in the European community: A (proposal for a) re-reading of the key defining elements in the light of EC law, and the scope for a slightly “refined” definition [PDF]
This papers, written at the occasion of the 50th anniversary of the EC Treaty and at a time of perceived importance of corporate governance at a world-wide level, offers an answer to the question whether a conception about the corporate objective and ...
Cerioni, L
core
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Guide to Geographical Indications: Linking Products and Their Origins (Summary) [PDF]
Geographical Indications present significant opportunities for differentiating products or services that are uniquely related to their geographic origin. While they can offer many positive economic, social, cultural, and even environmental benefits, they
Giovannucci, Daniele +4 more
core +1 more source
Indications of a sub-linear and non-universal Kennicutt-Schmidt relationship
We estimate the parameters of the Kennicutt-Schmidt (KS) relationship, linking the star formation rate (Sigma_SFR) to the molecular gas surface density (Sigma_mol), in the STING sample of nearby disk galaxies using a hierarchical Bayesian method.
Bigiel, Frank +7 more
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source

