Results 121 to 130 of about 174,544 (303)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2023–2024

open access: yesEFSA Journal
This report presents the main findings of the 2023–2024 harmonised antimicrobial resistance (AMR) monitoring in Salmonella spp., Campylobacter jejuni and Campylobacter coli from humans, food‐producing animals (broilers, laying hens, fattening turkeys ...
European Food Safety Authority (EFSA)   +1 more
doaj   +1 more source

Natural soil reservoirs for human pathogenic and fecal indicator bacteria

open access: yes, 2015
EAMERSUBSoils receive inputs of human pathogenic and indicator bacteria through land application of animal manures or sewage sludge, and inputs by wildlife.
Piveteau, Pascal   +8 more
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Action of autochthonous bacteria on the decay of enteric viruses in groundwater

open access: yes, 2006
With global freshwater supplies under pressure, viable water reuse methods are being examined to assist in improving water supplies. Municipal effluent is an ideal source for water reclamation as it is consistent in quality and quantity.
Wall, Katrina Joy
core  

Identifying Pollutant Sources in Tidally Mixed Systems:  Case Study of Fecal Indicator Bacteria from Marinas in Newport Bay, Southern California

open access: yes, 2016
This study investigates the contribution of several marinas to fecal indicator bacteria impairment in Newport Bay, a regionally important tidal embayment in southern California.
Youngsul Jeong (2438860)   +5 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

The Effects of Pretreatments on qPCR Detection of Bacteria ? Bacteria Indicator, Enterococcus as a Model

open access: yesJournal of Microbial & Biochemical Technology, 2015
Current recreational water guidelines (e.g. USEPA and WHO) recommend enterococci as the indicator for both freshwaters and marine waters. Culture-based method has been used for decades to quantify the presence of enterococci. In year 2012, USEPA guideline for recreational water included qPCR as the alternative method to detect enterococci.
openaire   +1 more source

Coliform bacteria and other potential indicator organisms in a pond.

open access: yes, 1976
Waters containing enteropathogenic microorganisms (i.e., Salmonella, Shigella) are considered unsafe for human consumption. Traditionally, indicator bacteria have been utilized for the assess- ment of bacteriologically unsafe waters.
Clymore, Gary Lee.
core  

General and Host-Associated Fecal Indicator Bacteria at Chicago Beaches

open access: yes, 2019
Waterborne illness resulting from surface water recreation on lakes, oceans, and rivers is a significant public health problem. Exposure to enteric bacteria, viruses, and protozoa are the main causes of swimming-related outbreaks of gastrointestinal ...
Abhilasha Shrestha (8973650)
core   +1 more source

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