Results 101 to 110 of about 235,503 (259)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Throughflow centrality is a global indicator of the functional importance of species in ecosystems

, 2012
To better understand and manage complex systems like ecosystems it is critical to know the relative contribution of system components to system functioning. Ecologists and social scientists have described many ways that individuals can be important; This
Abarca-Arenas, Allen, Allesina, Allesina, Allesina, Allesina, Almunia, Bailey, Bailey, Baird, Baird, Baird, Baird, Baird, Baird, Barabási, Baranyi, Bauer, Bodin, Bodini, Bonacich, Bonacich, Borgatti, Borgatti, Borgatti, Borrett, Borrett, Borrett, Borrett, Borrett, Burkhard, Cale, Caswell, Chen, Christian, Dale, Dayton, De Groot, Ellison, Estrada, Estrada, Fann, Fath, Fath, Fath, Fath, Fath, Fath, Fawcett, Finn, Finn, Freeman, Freeman, Friedkin, Gardner, Gondkar, Guimarães, Gunderson, Hahn, Hannon, Heymans, Heymans, Hines, Hooper, Hubbell, Ibarra, Jones, Jordán, Jordán, Jordán, Jørgensen, Jørgensen, Jørgensen, Jørgensen, Kennedy, Koschützki, Krause, Kritz, Lawton, Leontief, Leontief, Lindeman, Link, Loreau, Lotka, Martín González, Miehls, Miehls, Mills, Monaco, Müller, Müller, Newman, Odum, Odum, Odum, Paine, Patten, Patten, Pimm, Pinnegar, Power, Ray, Reed, Rittel, Ruhnau, Saavedra, Salas, Sandberg, Sazima, Scharler, Schneider, Schramski, Scotti, Stuart R. Borrett, Suh, Szyrmer, Ulanowicz, Ulanowicz, Ulanowicz, Ulanowicz, Valente, Walker, Walsh, Wasserman, Whipple, Whittaker, Wilkinson, Zhang, Zhang   +129 more
core   +1 more source

Bacterial Pathogen Occurrence and Persistence in Livestock Mortality Biopiles

Resources, 2017
Properly managed biopiles can be used for slaughterhouse-residual degradation and bacterial pathogen inactivation, which otherwise represent a major health risk in the environment.
Robert Michitsch, Robert Gordon, Rob Jamieson, Glenn Stratton   +3 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Breeding of broad-spectrum bacteriocin-producing lactic acid bacteria in traditional fermented dairy products [PDF]

Zhongguo niangzao
To breed broad-spectrum bacteriocin-producing lactic acid bacteria, 96 strains of lactic acid bacteria isolated and purified from tradition fermented dairy products in Gansu province were screened by agar diffusion assay, and the bacteriocin-producing ...
LIU Caiyun, MA Heping, ZHANG Wenqi, WANG Jie, PENG Zhangpu, SHAO Jianning
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Preliminary evaluation of probiotic properties of Lactobacillus strains isolated from Sardinian dairy products [PDF]

, 2014
Twenty-three Lactobacillus strains of dairy origin were evaluated for some functional properties relevant to their use as probiotics. A preliminary subtractive screening based on the abilities to inhibit the growth of microbial pathogens and hydrolyze ...
Conti S, Cosentino S, Deiana M, Deplano M, Fadda ME, Melis MP, Pisano MB, Viale S   +7 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Characteristics of Community and Healthcare Associated Methicillin Resistant Staphylococcus aureus [PDF]

, 2016
Undergraduate ...
Cargill, Michael
core   +1 more source