Results 91 to 100 of about 174,544 (303)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Counts of Air-Borne Bacteria as Indices of Air Hygiene [PDF]

Epidemiology and Infection, 1956
An attempt has been made to assess the value of counts of bacteria in the air of occupied rooms as indices of the risks of air-borne cross-infection in these rooms. Data collected during a field trial of ultra-violet irradiation in schoolrooms have been analysed to establish the correlation between counts of Streptococcus salivarius or of the general ...
O M, LIDWELL, D D, REID, R E, WILLIAMS
openaire   +2 more sources

Disinfection, Recontamination and Regrowth of Indicator Bacteria in a Wastewater Sludge Heat Treatment System

, 1988
The largest sewage treatment plant in Hawaii produces 25,400 kg/day of primary sludge that is heat-treated (190°C) under 330 psig for 3 0 min. Although this treatment should result in a sterilized sludge product, the final sludge cake often contains high
Philip C. Loh, Roger S. Fujioka, Wesley M. Hirano   +2 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Chlorination of Indicator Bacteria and Viruses in Primary Sewage Effluent [PDF]

Applied and Environmental Microbiology, 2003
ABSTRACT Wastewater disinfection is used in many countries for reducing fecal coliform levels in effluents. Disinfection is therefore frequently used to improve recreational bathing waters which do not comply with microbiological standards. It is unknown whether human enteric viruses (which are responsible for waterborne disease)
Tree, Julia A., Adams, Martin R., Lees, David N.   +2 more
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Exploring the potential for oxygen production by cable bacteria in the deep sediment through the investigation of amoA gene expression

, 2023
noneThis thesis aims to investigate the potential for oxygen production by cable bacteria in the deep sediment. To accomplish this, an indirect approach was used, specifically studying the expression of the amoA gene, belonging to the Nitrosomonas genus,
RRUCI, ERINDA
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Comparative Disinfection of Indicator Bacteria and Poliovirus by Chlorine Dioxide

, 1986
The effectiveness of ClO2 to disinfect poliovirus and indicator bacteria in clean water and sewage was determined. Clostridiumperfringens was the most resistant to disinfection by ClO2, followed by poliovirus, s.
B. S. Yoneyama, R. S. Fujioka, M. A. Dow
core   +1 more source