Results 51 to 60 of about 177,671 (276)

CERVIS: Cervical Cancer Early Response Visual Identification System [PDF]

, 2019
The goal of CERVIS is to make a substantial, positive impact in the cervical cancer screening space through the development of a minimally invasive, cost effective solution that enables women in low-resource settings to test for cervical cancer on a ...
Hultquist, Claire, Lanoha, Julia, McDonagh, Rosie, McNamara, Hallie   +3 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

‘Giant’ magnetoresistance in obliquely co-evaporated Co-Ag films [PDF]

, 1993
Magnetoresistance (MR) measurements at room temperature have been performed on obliquely (co-) evaporated Ag-Co films deposited at room- and elevated-temperatures. The ‘giant’ magnetoresistance ratio (max.
Haan, P. de, Kranenburg, H. van, Lodder, J.C.   +2 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Reliability of cerebral blood flow measurements by transcerebral double-indicator dilution technique

European Journal of Anaesthesiology, 2001
The recently developed transcerebral double-indicator dilution technique has proven to be a feasible monitoring alternative to measure global cerebral blood flow at the bedside. However, the short-term repeatability of transcerebral double-indicator dilution measurements has not yet been investigated.
Mielck, F., Wietasch, G., Weyland, A., Buhre, W., Meier-Theile, C., Hoeft, A., Sonntag, H.   +6 more
openaire   +4 more sources

The use of invasive techniques, angiography and indicator dilution, for quantification of valvular regurgitations [PDF]

European Heart Journal, 1987
Angiographic techniques have been used for the quantification of mitral or aortic and rarely tricuspid regurgitation. Mitral or aortic regurgitant volume per beat and the regurgitation fraction (fao and fm, respectively) are obtained from the angiographic determination of total left ventricular stroke volume (TSV) and forward stroke volume (FSV ...
Krayenbuehl, H P, Ritter, M, Hess, O M, Hirzel, H   +3 more
openaire   +2 more sources

Flower Biology of Two Diospyros Species Neighborly Live at Csc Area: Do Pollen Viability and Tube Growth Rate Shire Endemic Distribution [PDF]

, 2008
Aims of study were to compare flower structure, pollen viability and pollen tube growth rate of two Diospyros species neighborly live in Cibinong Science Centre (CSC) park, Diospyros blancoi and D.
Rachman, E. (Erlin)
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

First light of the VLT planet finder SPHERE. I. Detection and characterization of the sub-stellar companion GJ 758 B [PDF]

, 2015
GJ758 B is a brown dwarf companion to a nearby (15.76 pc) solar-type, metal-rich (M/H = +0.2 dex) main-sequence star (G9V) that was discovered with Subaru/HiCIAO in 2009.
Antichi, J., Baruffolo, A., Baudino, J. -L., Baudoz, P., Beust, H., Beuzit, J. -L., Blanchard, P., Boccaletti, A., Bonnefoy, M., Buenzli, E., Carle, M., Chauvin, G., Claudi, R., Costille, A., D'Orazi, V., Delboulbe, A., Desidera, S., Dohlen, K., Dominik, C., Feldt, M., Fusco, T., Galicher, R., Ginski, C., Girard, J., Giro, E., Gluck, L., Gratton, R., Gry, C., Hagelberg, J., Henning, T., Hubin, N., Hugot, E., Janson, M., Jaquet, M., Kasper, M., Lagrange, A. -M., Langlois, M., Le Mignant, D., Llored, M., Madec, F., Maire, A. -L., Malo, L., Martinez, P., Mawet, D., Mesa, D., Milli, J., Mouillet, D., Moulin, T., Moutou, C., Origne, A., Pavlov, A., Perret, D., Petit, C., Pragt, J., Puget, P., Rabou, P., Rochat, S., Roelfsema, R., Salasnich, B., Salter, G., Sauvage, J. -F., Schmid, H. -M., Sevin, A., Siebenmorgen, R., Smette, A., Stadler, E., Suarez, M., Thalmann, C., Turatto, M., Udry, S., Vakili, F., Vigan, A., Wahhaj, Z., Weber, L., Wildi, F., Zurlo, A.   +75 more
core   +2 more sources