Results 131 to 140 of about 1,134,722 (269)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
World Development Indicators 2006
, 2006 The developing world has made remarkable progress. The number of people living in extreme poverty on less than $1 a day has fallen by about 400 million in the last 25 years.
World Bank
core +1 more source
Current Developments in NutritionBackground: Assessing dietary intake and receipt of nutrition services is essential for monitoring health and development, yet accurately measuring these indicators via population-based surveys remains challenging.
Sorrel ML Namaste +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A quantitative framework for selecting and validating food web indicators
, 2018 Finding suitable state indicators is challenging and cumbersome in stochastic and complex ecological systems. Typically, a great focus is given to criteria such as data availability, scientific basis, or measurability.
Saskia A. Otto +9 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Open Access Journal of ContraceptionSyahmida Syahbuddin Arsyad,1 Laili Rahayuwati,2 Rahmadewi,1 Septi Nurhayati,1 Arga Nugraha,3 Darojad Nurjono Agung Nugroho,4 Oktriyanto,1 Mugia Bayu Rahardja,1 Yanu Endar Prasetyo,1 Yanti Astrelina Purba,1 Ruth Meilianna,1 Indra Murty Surbakti,5 Wahyu ...
Syahbuddin Arsyad S +13 more
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2018 The article is devoted to the analysis of the existing indicators of the effectiveness of navigation systems and vessel traffic management, which led to the conclusion that the probability of performing a task without emergency events is the most ...
Oleksiy V. Danick +2 more
doaj