Results 131 to 140 of about 2,689,332 (309)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Chapter 2. Higher Education in Science and Engineering
, 2019 This chapter focuses on the development of human capital in Science and Engineering (S&E) through higher education. Postsecondary education provides the advanced skills needed for an educated citizenry, a competitive workforce, and—in the case of ...
Science And Engineering Indicators 2018 +1 more
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Selection and modeling sustainable urbanization indicators: A responsibility-based method
, 2015 The responsibility borne by governmental departments measured by a set of indicators is a key factor affecting the performance of urban sustainability. Thus, responsibility analysis can guide the selection of sustainability indicators.
Song, Xiangnan +3 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Quality Assurance Policies and Indicators for Long-Term Care in the European Union. ENEPRI Policy Brief No. 11, February 2012 [PDF]
, 2012 This Policy Brief summarises findings from Work Package (WP) 5 of the ANCIEN project and its three objectives: first, collecting comprehensive information on national quality assurance policies and indicators in LTC systems in 15 EU member states; second,
Dandi, Roberto
core
Open Access Journal of ContraceptionSyahmida Syahbuddin Arsyad,1 Laili Rahayuwati,2 Rahmadewi,1 Septi Nurhayati,1 Arga Nugraha,3 Darojad Nurjono Agung Nugroho,4 Oktriyanto,1 Mugia Bayu Rahardja,1 Yanu Endar Prasetyo,1 Yanti Astrelina Purba,1 Ruth Meilianna,1 Indra Murty Surbakti,5 Wahyu ...
Syahbuddin Arsyad S +13 more
doaj
Indications and Contra Indications for E.C.T. [PDF]
Postgraduate Medical Journal, 1954 openaire +2 more sources