Results 101 to 110 of about 142,903 (317)
Guidelines for the use of cell lines in biomedical research [PDF]
Cell-line misidentification and contamination with microorganisms, such as mycoplasma, together with instability, both genetic and phenotypic, are among the problems that continue to affect cell culture.
Capes-Davis, A.+11 more
core +2 more sources
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
The design of a quality improvement dashboard for monitoring spinal cord and column injuries
Background: Interactive dashboards are a powerful tool for dynamic visualization and monitoring of patient performance and serve as a useful to for optimal decision-making.
Zahra Azadmanjir+6 more
doaj
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Effective monitoring of the time‐temperature history of biological reagents, chemical drugs, and perishable foods during cold chain storage is crucial for ensuring their quality and efficacy. Time‐temperature indicators (TTIs) are developed to assess the
Donghui Kou+4 more
doaj +1 more source
High-throughput malaria serosurveillance using a one-step multiplex bead assay
Background Serological data indicating the presence and level of antibodies against infectious disease antigens provides indicators of exposure and transmission patterns in a population. Laboratory testing for large-scale serosurveys is often hindered by
Eric Rogier+18 more
doaj +1 more source
Environmental impact assessment of Polyester Fiber Asphalt Mixture [PDF]
In the context of the dual carbon policy, environmental protection has become pressing need of the times. Polyester fiber asphalt mixture is gradually replacing traditional inefficient ordinary asphalt mixture due to its excellent performance.
Xie Yuanhao
doaj +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Improved real-time PCR assays for the detection of fecal indicator bacteria in surface waters with different instrument and reagent systems [PDF]
Shawn Siefring+4 more
openalex +1 more source