Results 101 to 110 of about 152,483 (320)

Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer. [PDF]

, 2015
The cancer stem cell hypothesis, that a small population of tumour cells are responsible for tumorigenesis and cancer progression, is becoming widely accepted and recent evidence has suggested a prognostic and predictive role for such cells. Intra-tumour
Banerji, CR, Caldas, C, Severini, S, Teschendorff, AE   +3 more
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Reagent-free detection of Plasmodium falciparum malaria infections in field-collected mosquitoes using mid-infrared spectroscopy and machine learning

Scientific Reports
Field-derived metrics are critical for effective control of malaria, particularly in sub-Saharan Africa where the disease kills over half a million people yearly.
Emmanuel P. Mwanga, Prisca A. Kweyamba, Doreen J. Siria, Issa H. Mshani, Idrisa S. Mchola, Faraja E. Makala, Godian Seleman, Said Abbasi, Sophia H. Mwinyi, Mario González-Jiménez, Klaas Waynne, Francesco Baldini, Simon A. Babayan, Fredros O. Okumu   +13 more
doaj   +1 more source

Screening of psycho-oncologic issues: Validation of a checklist

Psicooncologia, 2014
Objective: Develop and validate a Checklist of psycho-oncologic issues (LC-Psycho-onco) for oncologic patients in treatment. Method: We included 200 patients at the National Cancer Institute (INCAN).
Oscar Galindo Vázquez, Mayelli Muñóz Martínez, Sofía Campos Ugalde, Edith Rojas Castillo, María Cristina Maya Vázquez, Salvador Alvarado Aguilar   +5 more
doaj   +1 more source

The importance of mineralogical knowledge in the sustainability of artisanal gold mining: a mid-south Peru case [PDF]

, 2019
Mineralogy and gold processing techniques from several mining areas of the Nazca-Ocoña gold belt, Mid-South Peru, were investigated to assess the efficiency of gold extraction methods in relation to their mineralogy.
Alfonso Abella, María Pura, Anticoi Sudzuki, Hernán Francisco, Bascompta Massanes, Marc, García-Vallès, Maite, Henao, Laura, Palacios Ubach, Silvia, Yubero de Mateo, Maria Teresa, Yáñez González, Juan Alberto   +7 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Treatment and Recycling of Tungsten Beneficiation Wastewater: A Review

Separations
The large amount of wastewater containing various pollutants generated during the tungsten beneficiation process has become a bottleneck for the sustainable development of tungsten mining enterprises.
Wenxia Zhu, Jianhua Kang, Danxian Zhang, Wei Sun, Zhiyong Gao, Haisheng Han, Runqing Liu   +6 more
doaj   +1 more source

Assessment of porcine endogenous retrovirus transmission across an alginate barrier used for the encapsulation of porcine islets [PDF]

, 2018
BACKGROUND: Subcutaneous implantation of a macroencapsulated patch containing human allogenic islets has been successfully used to alleviate type 1 diabetes mellitus (T1DM) in a human recipient without the need for immunosuppression.
Crossan, Claire, Gianello, Pierre, Mourad, Nizar I., Scobie, Linda, Smith, Karen   +4 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source