Benefits of topical indigo naturalis nanofibrous patch on psoriatic skin: A transdermal strategy for botanicals [PDF]
Materials Today Bio, 2023 Indigo naturalis (IN) has been extensively used as a topical treatment for psoriasis. However, clinical applications of IN in ointment were hampered by its limited transdermal efficiency and dark stains.
Pengyu Wang +11 more
doaj +2 more sources
One-year clinical efficacy and safety of indigo naturalis for active ulcerative colitis: a real-world prospective study [PDF]
Intestinal Research, 2022 Background/Aims Recent studies suggested a favorable effect of indigo naturalis (IN) in inducing remission for refractory ulcerative colitis (UC), however, the maintenance effect of IN for patients with UC remains unknown.
Yuichi Matsuno +17 more
doaj +2 more sources
Indigo Naturalis regulates the gut microbiota to increase SCFAs content and improve ulcerative colitis lesions [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundThe global prevalence of ulcerative colitis (UC) is approximately 5 million, and the incidence is on the rise. The gut microbiota (GM) plays a key role in the pathogenesis and progression of UC.
Xiang-Yi Zhan +7 more
doaj +2 more sources
Traditional mineral medicine realgar and Realgar-Indigo naturalis formula potentially exerted therapeutic effects by altering the gut microbiota [PDF]
Frontiers in Microbiology, 2023 IntroductionRealgar has a long history ofuse in traditional medicines. However, the mechanism through which Realgar or Realgar-Indigo naturalis formula (RIF) exert therapeutic effects is only partially understood.MethodsIn this study, 60 feces and 60 ...
Lu Luo +12 more
doaj +2 more sources
Testing for Genotoxicity of Indigo Naturalis Assessed by Micronucleus Test [PDF]
Natural Product Communications, 2010 In the field of cosmetic dyes, used for coloring the hair and skin, there is a clear tendency to replace the widely used synthetic dyes by natural colorants, such as henna and mixtures of henna with indigo.
Luca Dominici +4 more
doaj +5 more sources
Oral Realgar-Indigo Naturalis Formula Plus Retinoic Acid for Acute Promyelocytic Leukemia [PDF]
Frontiers in Oncology, 2021 Treatment paradigm of acute promyelocytic leukemia (APL) is by no mean the most remarkable story of cancer therapy. Recently, the advent of oral arsenic formulations (oral-arsenic trioxide and Realgar-Indigo Naturalis formula (RIF)) based regimens may ...
Yinjun Lou +3 more
doaj +2 more sources
Prospective feasibility study of indigo naturalis ointment for chemotherapy-induced oral mucositis. [PDF]
BMJ Support Palliat Care, 2021 ObjectivesIndigo naturalis, a herbal medicine effective against ulcerative colitis, exhibits anti-inflammatory effects and induces interleukin-22-mediated antimicrobial peptide production. Anti-inflammatory activity and the prevention of secondary infection are essential for the management of chemotherapy-induced oral mucositis (CIOM); therefore, we ...
Hirata K +9 more
europepmc +4 more sources
Efficacy of Indigo Naturalis Therapy for Ulcerative Colitis: A Case Series. [PDF]
Intern Med, 2019 Objective Indigo naturalis (IN) is a traditional Chinese medicine that has recently been reported to be effective for ulcerative colitis (UC). The aim of this study was to evaluate the efficacy and safety of IN. Methods We performed a retrospective observational study for 14 patients with UC treated with IN from October 2015 to December 2016.
Urushikubo J +9 more
europepmc +4 more sources
Indigo Naturalis (青黛) Comes from Blue, but it Excels Blue
Chinese Medicine and Culture, 2019 Indigo naturalis (青黛) is also called “indigo flower,” “bright cyan,” and “cyan clam powder.” The alias “indigo flower” shows its complex progress about producing dyes.
Tianwen Yao, Baican Yang
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Indigo naturalis for inflammatory bowel disease: evidence from animal studies and molecular mechanisms [PDF]
Frontiers in PharmacologyBackgroundIndigo naturalis (IN) has been extensively used in prescriptions of traditional Chinese medicine to treat inflammatory bowel disease (IBD), particularly ulcerative colitis (UC).
Jie Hu +7 more
doaj +2 more sources