Results 191 to 200 of about 61,847 (299)

Metformin attenuates metabolic insulin sensitivity and insulin‐stimulated carbohydrate oxidation after high‐intensity exercise training in adults at risk for metabolic syndrome

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2941-2952, April 2026.
Abstract Aims Mixed evidence exists on whether metformin adds to or attenuates the insulin‐sensitising effects of exercise. To date, no studies have tested whether metformin differentially impacts exercise training intensity–mediated insulin sensitivity.
Steven K. Malin   +7 more
wiley   +1 more source

Exploring Cation Selection and Disorder Within Entropy‐Driven A6B2O17 (A = Zr/Hf, B = Nb/Ta) Oxides

open access: yesJournal of the American Ceramic Society, Volume 109, Issue 4, April 2026.
ABSTRACT We investigate the local atomic and electronic structure, thermodynamic stability, and defect chemistry of A6B2O17 (A = Zr/Hf, B = Nb/Ta) oxides using first‐principles density functional theory (DFT) calculations. We examine both ordered unit cells as well as fully disordered special quasirandom structures to clearly discern the effects of ...
Jacob T. Sivak   +3 more
wiley   +1 more source

Lack of GPNMB Is Associated With Altered Lipid and Glucose Metabolism and Disrupted Diurnal Hepatic Glycogen Regulation

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Loss of GPNMB function in mice fed a high‐fat/high‐fructose diet aggravated adiposity and dyslipidemia while preserving systemic glucose tolerance. This phenotype was associated with impaired hepatic AKT–FOXO1 signaling, increased NF‐κB activation, altered glycogen metabolism, and rhythmic disturbances in energy expenditure and clock gene expression ...
Eliz Maria de Oliveira Furtado   +15 more
wiley   +1 more source

The correlation between indirect calorimetry data and the metabolic syndrome development in men and women. [PDF]

open access: yesJ Diabetes Metab Disord
Roudi F   +9 more
europepmc   +1 more source

Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley   +1 more source

Development and Investigation of the Synergistic Properties of Latex (Hevea brasiliensis)/Poly (Vinyl Alcohol) as a Potential Dermal Dressing

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 10, March 10, 2026.
Development and physicochemical and biological characterization of Latex/PVA membranes at different ratios. ABSTRACT Research on dermal dressings has become increasingly important due to the need for affordable, effective, and accessible alternatives to costly and invasive conventional treatments, with materials such as Latex from Hevea brasiliensis ...
Jessica Asami   +6 more
wiley   +1 more source

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