Results 151 to 160 of about 1,223,886 (257)

Interleukin‐1α Mediates Pancreatic Fibroblast Activation, Regulates Immune Cell Recruitment and Fibrosis in Acute and Chronic Pancreatitis

open access: yesAdvanced Science, EarlyView.
During pancreatitis, IL‐1α is released from necrotic acinar cells. In response to IL‐1α, pancreatic fibroblasts release chemokines and cytokines that regulate the recruitment of immune cells to the damaged organ. Furthermore, IL‐1α primes fibroblasts, resulting in increased tissue fibrosis during chronic pancreatitis.
Hala Mazloum   +13 more
wiley   +1 more source

Quantification of amygdalin in various seeds using indirect competitive ELISA

open access: yes, 2007
아미그달린(amygdalin)은 시안배당체(cyanogenic glycoside comp -ound) 물질로 보통 과일의 씨앗이나 견과류 그리고 몇몇 식물에 존재한다. Emulsin에 의해 benzaldehyde, cyanide, 그리고 두 분자의 포도당으로 분해되는데, 여기서 cyanide는 신경독성 물질로 메스꺼움, 구토, 두통, cyanosis의 원인이 되며 심하면 죽음에 이르게 되므로 위험하다.
이수정
core  

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

open access: yesAdvanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen   +11 more
wiley   +1 more source

Development of an indirect ELISA for the detection of venezuelan equine encephalitis virus specific antibodies in horses. [PDF]

open access: yesPLoS One
Chevrier M   +18 more
europepmc   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao   +2 more
wiley   +1 more source

Elisa Lucinda: artigo 227 [Constituindo]

open access: yes, 2016
Ensino Fundamental::Séries Iniciais::Pluralidade CulturalEnsino Fundamental Final::Pluralidade CulturalApresenta vídeo da série Constituindo. Neste episódio a atriz Elisa Lucinda lê o artigo 227 da Constituição Federal do Brasil de 1988.
TV Câmara
core  

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu   +12 more
wiley   +1 more source

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