Results 91 to 100 of about 708,304 (217)

Material flow during the extrusion of simple and complex cross-sections using FEM [PDF]

open access: yes, 2005
This paper deals with the extrusion of rod and shape sections and uses a 3D finite element model analysis (FEM) to predict the effect of die geometry on maximum extrusion load.
Flitta, Isaac, Sheppard, Terry
core   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

open access: yesAdvanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang   +14 more
wiley   +1 more source

Modelling of Strain Field in Extrusion by Die Geometry

open access: yesEngineering Transactions, 1995
The strain distributions within the deformation zone and the total strain in the extruded product cross-sections for A1Cu4Mg alloy were determined. The visioplasticity method was used in calculations.
W. Libura
doaj  

Rheology of semi-solid fresh cement pastes and mortars in orifice extrusion [PDF]

open access: yes, 2013
Short fiber-reinforced semi-solid fresh cement pastes and mortars, tailored for extrusion, have much lower water-to-binder ratio and higher viscosity than normal cement pastes or mortars. The rheology of these pastes or mortars cannot be characterized by
Fan, Mizi   +7 more
core   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao   +2 more
wiley   +1 more source

Tumor Mechanical Remodeling via Bidirectional Calcium Redistribution Enables Deep Photothermal‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
A bidirectional calcium‑redistributing nanomodulator rewires intra‑extracellular calcium homeostasis to remodel tumor mechanical microenvironments. It softens tumor stroma to facilitate deep tissue penetration while stiffening tumor cells, evoking amplified immunogenic cell death and robust CTL infiltration, which achieves potent deep photothermal ...
Hongjuan Zhao   +9 more
wiley   +1 more source

Reflex Charging for Anion‐Derived Solid Electrolyte Interphase Formation

open access: yesAngewandte Chemie, EarlyView.
Reflex charging reprograms the electric double layer (EDL) during battery formation by periodically reversing electrode polarity, enabling persistent anion enrichment at the interface. This dynamic interfacial control shifts Li+ solvation toward anion‐coordinated states, promoting the formation of an inorganic‐rich, anion‐derived solid electrolyte ...
Gyeoul Seong   +9 more
wiley   +2 more sources

Sodium butyrate interrupts the maturation of oocytes and enhances the development of preimplantation embryos.

open access: yesPLoS ONE, 2019
Histone acetylation is one of the most important posttranslational modifications that contribute to transcriptional initiation and chromatin remodeling. In the present study, we aimed to investigate the effect of sodium butyrate (NaBu), a natural histone
Meng-Fei Yu   +3 more
doaj   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

open access: yesAdvanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng   +12 more
wiley   +1 more source

CO2 as a Redox Shuttle Enables Photocatalytic Dehydrogenative Decarbonylation of Biomass‐Derived Alcohols to Light Alkanes

open access: yesAngewandte Chemie, EarlyView.
A heterogeneous photocatalytic system has been developed that enables the dehydrogenative decarbonylation of primary alcohols under visible light using highly dispersed oxidic iron sites supported on aryl‐modified graphitic carbon nitride (Fe@f–gC3N4).
Jun Hu   +11 more
wiley   +2 more sources

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