Results 101 to 110 of about 2,266,638 (297)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Z-scan confocal method for indirect focus location

open access: yesAIP Advances, 2017
We present a new technique that we have defined as the z-scan confocal method to determine the location and size of the focal spot in a tightly focused ultrashort laser pulse.
Pablo Castro-Marín   +5 more
doaj   +1 more source

A COMPARATIVE STUDY REGARDING THE CALCULATION OF PRODUCTION COST BY THE TRADITIONAL-GLOBAL METHOD AND THE ABC METHOD ON AN ECONOMIC ENTITY IN ROMANIA [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2020
Through this paper, the author using the method of observation, economic analysis and empirical research tries to demonstrate the advantages and disadvantages of using modern methods versus traditional methods of calculating the costs.
ILEANA-SORINA RAKOS
doaj  

An Indirect Method of Micromagnetic Structure Estimation in Microwires. [PDF]

open access: yesNanomaterials (Basel), 2021
Alekhina I   +6 more
europepmc   +1 more source

Limit analysis problem and its penalization [PDF]

open access: yes, 2017
The contribution is focused on solution of the kinematic limit analysis problem within associative perfect plasticity. It is a constrained minimization problem describing a collapse state of an investigated body.
Sysala, Stanislav
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Hidden and Indirect (Probabilistically Estimated) Reputations - Hiper Method

open access: yesFoundations of Computing and Decision Sciences, 2015
It is a challenge to design a well balanced reputation system for an environment with millions of users. A reputation system must also represent user reputation as a value which is simple and easy to compare and will give users straightforward ...
Leszczyński Konrad, Zakrzewicz Maciej
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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