Results 41 to 50 of about 424,126 (299)

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Generation of Monoclonal Antibodies against Variable Epitopes of the M Protein of Rabies Virus

Viruses, 2019
Rabies virus (RABV), the causative agent of rabies, is highly neurovirulent for warm-blooded animals with a mortality rate of up to 100%. The RABV matrix protein (M) is required for virus particle assembly and budding.
Jie Liu, Wen Zhao, Wanting He, Ningning Wang, Jingyin Su, Senlin Ji, Jian Chen, Dong Wang, Jiyong Zhou, Shuo Su   +9 more
doaj   +1 more source

Sequence diversity and evolution of infectious bursal disease virus in Iraq [version 2; peer review: 2 approved]

F1000Research, 2021
Background: Infectious Bursal Disease (IBD) is a highly infectious disease which causes huge economic losses to the poultry industry due to the direct impact of the illness and indirect consequences such as decreasing the general immunity of the flock ...
Ali Hadi Abbas, Haider Abas AL saegh, Furkan Sabbar ALaraji   +2 more
doaj   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

Metagenomic analysis of a a southern maritime Antarctic soil [PDF]

, 2012
Our current understanding of Antarctic soils is derived from direct culture on selective media, biodiversity studies based on clone library construction and analysis, quantitative PCR amplification of specific gene sequences and the application of ...
David Anthony Pearce, Thorne, Michael A. S., Wellington, E. M., Andy Hodson, Kevin eNewsham, Michael A. S. Thorne, Calvo-Bado, Leo, Laskaris, Paris, Paris Laskaris, Calvo-Bado, Leo A., Hodson, A., Leo Calvo-Bado, Pearce, D. A., Elizabeth M H Wellington, Wellington, Elizabeth M., Thorne, Michael A.S., Thorne, Michael, Leo eCalvo-Bado, Paris eLaskaris, Calvo-Bado, L., Martin Krsek, Andy Hodson, Kevin K. Newsham, Thorne, M. A. S., Elizabeth M. Wellington, Laskaris, P., Pearce, David, Hodson, Andrew J., Martin eKrsek, Pearce, David A., David A. Pearce, Michael eThorne, Andy eHodson, Newsham, K. K., Krsek, M., Krsek, Martin, Wellington, Elizabeth, David A. Pearce, Newsham, Kevin, Wellington, E. M. H., Newsham, Kevin K., Hodson, Andy   +41 more
core   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

The natural history of biocatalytic mechanisms

, 2014
JBOM and NN thank the Scottish Universities Life Science Alliance (SULSA) http://www.sulsa.ac.uk/ and Scottish Funding Council (SFC) http://www.sfc.ac.uk/ for financial support.
Gustavo Caetano-Anollés (65405), Caetano-Anolles, Gustavo, Neetika Nath, Neetika Nath (569834), Nath Neetika, John B. O. Mitchell (22057), Caetano-Anollés Gustavo, Mitchell John B. O., Gustavo Caetano-Anollés, Nath, Neetika, Mitchell, John B. O., John B O Mitchell   +11 more
core   +1 more source

Dengue virus 3 genotype I (GI) lineage 1 (L1) isolates elicit differential cytopathic effect with syncytium formation in human glioblastoma cells (U251)

Virology Journal, 2023
Background Dengue virus (DENV) is a Flaviviridae member classified into four antigenically distinct serotypes (DENV 1, 2, 3, and 4) and further subdivided genotypes. DENV3 is subdivided into four or five genotypes, depending on the classification adopted.
Adriana de Souza Andrade, Sofia Oliveira Campos, Jamile Dias, Marco Antônio Campos, Erna Geessien Kroon   +4 more
doaj   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Seroconversion for infectious pathogens among UK military personnel deployed to Afghanistan, 2008-2011. [PDF]

, 2014
Military personnel are at high risk of contracting vector-borne and zoonotic infections, particularly during overseas deployments, when they may be exposed to endemic or emerging infections not prevalent in their native countries.
Andrew Bosworth, Hewson, Roger, Edmund N.C. Newman, Tim Brooks, Wright, Deborah, Hannah Bridge, Newman, Edmund NC, Andrew Green, Roger Hewson, Lisa Jameson, Ross, David, Green, Andrew, Osborne, Jane, Jenny Hayward-Karlsson, Mark S. Bailey, Bailey, Mark S, Brooks, Tim, Johnstone, Penelope, Deborah Wright, Penelope Johnstone, Rebecca Hatch, Jameson, Lisa, Bosworth, Andrew, Bridge, Hannah, Hatch, Rebecca, Hayward-Karlsson, Jenny, Jane Osborne, David Ross   +27 more
core   +1 more source