Results 61 to 70 of about 424,126 (299)

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Phylogenetic and functional gene microarray analysis demonstrates direct and indirect mechanisms for sustained chromium bio-immobilization [PDF]

, 2007
Background: During a field-scale chromium treatability study, a single dose of a slow release electron donor (HRC) was applied to a contaminated aquifer to stimulate microbial reductive precipitation of hexavalent chromium Cr(VI).
Brodie, E.L., Newcomer, D.R., Joyner, D., Nostrand, Joy D. Van, Hazen, T.C., Faybishenko, B., Borglin, Sharon, Conrad, M.E., Zhou, J., Long, P.E., Chakraborty, R., Andersen, G.L.   +11 more
core  

Phenotypic evolution and hidden speciation in Candidula unifasciata ssp. (Helicellinae, Gastropoda) inferred by 16S variation and quantitative shell traits

, 2006
In an effort to link quantitative morphometric information with molecular data on the population level, we have analysed 19 populations of the conchologically variable land snail Candidula unifasciata from across the species range for variation in ...
Pfenninger, Markus, Magnin, Frédéric
core   +1 more source

Reassortment and genomic analysis of a G9P[8]-E2 rotavirus isolated in China

Virology Journal, 2023
Objective To isolate a prevalent G9P[8] group A rotavirus (RVA) (N4006) in China and investigate its genomic and evolutionary characteristics, with the goal of facilitating the development of a new rotavirus vaccine.
Rui Peng, Dandi Li, Jindong Wang, Guangping Xiong, Mengxuan Wang, Dan Liu, Yuhang Wei, Lili Pang, Xiaoman Sun, Huiying Li, Xiangyu Kong, Saleha Shahar, Zhaojun Duan   +12 more
doaj   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Human pediculosis, a global public health problem

Infectious Diseases of Poverty, 2022
Background Human pediculosis is caused by hematophagous lice, which are transmitted between individuals via direct and/or indirect contact. Despite the public health importance of louse infestation, information concerning the global burden of pediculosis
Yi-Tian Fu, Chaoqun Yao, Yuan-Ping Deng, Hany M. Elsheikha, Renfu Shao, Xing-Quan Zhu, Guo-Hua Liu   +6 more
doaj   +1 more source

Natural Variation of COLD and CATECHINS REGULATOR 1 Coordinately Fine‐Tunes Cold Tolerance and Tea Quality in Tea Plants

Advanced Science, EarlyView.
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang, Wei Tong, Qiong Wu, Didi Wu, Yanrui Zhang, Qijuan Gao, Fangdong Li, Zhaoliang Zhang, Wenjie Wang, Chuankui Song, Enhua Xia   +10 more
wiley   +1 more source

Comparative study of the effectiveness and limitations of current methods for detecting sequence coevolution

Bioinform., 2015
Motivation: With rapid accumulation of sequence data on several species, extracting rational and systematic information from multiple sequence alignments (MSAs) is becoming increasingly important.
Wenzhi Mao, Cihan Kaya, Anindita Dutta, A. Horovitz, I. Bahar   +4 more
semanticscholar   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Mannose-binding lectin 2 polymorphisms do not influence frequency or type of infection in adults with chemotherapy induced neutropaenia. [PDF]

, 2012
BACKGROUND: Mannose-binding Lectin protein (MBL) has been suggested to be relevant in the defence against infections in immunosuppressed individuals.
Öhrmalm, Lars, Michelle Wong, Ohrmalm, L, Öhrmalm L., Lars Öhrmalm, Aust Carl, Tolfvenstam, Thomas, Tolfvenstam T., Hibberd, Martin, Wong, Michelle, Martin Hibberd, Hibberd M., Broliden K., Tolfvenstam, T,, Hibberd, M, Kristina Broliden, Thomas Tolfvenstam, Broliden, K,, Broliden, Kristina, Hibberd Martin, Broliden Kristina, Aust, C,, Wong, M, Carl Aust, Aust C., Wong M., Tolfvenstam Thomas, Öhrmalm Lars, Wong Michelle, Aust, Carl   +29 more
core   +1 more source