Results 31 to 40 of about 11,622 (255)
Directive Speech Acts in The Short Film “Makr” by Hana Kazim (George Yule`s Pragmatic Study)
Tarling, 2023 This research discusses directive speech acts in the short film Makr. A directive speech act is a type of speech act that is used by the speaker to order the hearer to do something.
Febyanti Fadhliatul
doaj
Function of the Speech acts in an allegory from Mathnavi-e Ma’navi [PDF]
زبان پژوهیIntroduction A speech act is basically an action that is realized through uttering a statement. According to speech act theory, the unit of linguistic communication is not the pronunciation of words and sentences; rather, such pronunciation is only part
Hamid Kamali Moqadam +2 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
“I Hear the Cry, but I Do Not See the Tears”: Indirectness in Bribery Negotiations
African Journal of Inter-Multidisciplinary StudiesThere is a relationship between crime and language, particularly crimes such as bribery, which are perpetuated through the use of language. These language-based crimes are often articulated indirectly to afford the interlocutor’s denial should such a ...
Mampoi Irene Mabena +1 more
doaj +7 more sources
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
CLASSIFICATION AND WAYS OFEXPRESSION OF SUGGESTIVES
Sovremennye Issledovaniâ Socialʹnyh Problem, 2013 The article focuses on different classifications of speech acts called suggestives in the framework of speech acts theory on the basis of modern English literature.
Alexandra Michailovna Kochergan
doaj
EXPRESSIVE SPEECH ACTS IN GUILLERMO DEL TORO’S PINOCCHIO MOVIE (2022)
Jurnal SmartThis study analyzes the types and strategies of expressive speech acts in Guillermo del Toro’s Pinocchio (2022). Using qualitative descriptive method, the research analyzes dialogue containing expressive speech acts based on Searle’s (1979) speech act ...
Malika Arindi Putri, Ambar Pujiyatno
doaj +1 more source