A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source
Bridging Minds and Behaviours: Patient Empowerment Mediates Psychological Factors and Diabetes Self-Management. [PDF]
Liu S +7 more
europepmc +1 more source
Bacterial α‐diversity decreases, but stochasticity and community stability increase across the 15 m‐depth vertical profiles and along the degraded gradient within the active layer. The abundance and interaction of core taxa mainly control community stability in the active and permafrost layers, respectively.
Shengyun Chen +13 more
wiley +1 more source
Green transformational leadership and employees' green behavior: a cross-level moderated mediation study. [PDF]
Cao J, Sun H, Cao X, Ma H.
europepmc +1 more source
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
Digital Sleep Disruption: Unraveling the Network Structure of Technology Use and Sleep Problems Through Network Analysis. [PDF]
Gan H, Xu L, Tong C.
europepmc +1 more source
Gut-Derived Metabolites and Cognitive Health: Roles of Short-Chain Fatty Acids and Trimethylamine N-oxide. [PDF]
Gupta DK, Kumar R.
europepmc +1 more source
Variation in area proportion and mechanical properties between different subregions of ACL insertion: An in vitro biomechanical study in a porcine model. [PDF]
He K, Yang Q, Shi Q, Wang H, Cheng CK.
europepmc +1 more source
How Is Self-Compassion Associated with Prolonged Grief and Posttraumatic Stress After Bereavement? The Mediating Roles of Perceived Stigma and Anger. [PDF]
Jiang X, Mao Z, Wu Q, Tang S.
europepmc +1 more source
Twin Small RNAs and Divergent Fates: The Expansive Regulatory Networks of OmrA and OmrB. [PDF]
Konarska J +3 more
europepmc +1 more source

