Results 61 to 70 of about 18,856,199 (287)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Models of Individual Blue Stragglers

, 2014
This chapter describes the current state of models of individual blue stragglers. Stellar collisions, binary mergers (or coalescence), and partial or ongoing mass transfer have all been studied in some detail.
A. Hypki, A. Maeder, A. Procter Sills, A. Sills, A. Sills, A. Sills, A. Sills, A. Sills, A. Sills, B. Tian, C. A. Nelson, C. D. Bailyn, D. Lauterborn, E. Gaburov, E. Glebbeek, E. Glebbeek, E. Glebbeek, E. Glebbeek, E. L. Sandquist, F. D’Antona, J. A. Ouellette, J. C. Lombardi Jr, J. C. Lombardi Jr, J. C. Lombardi Jr, J. G. Hills, J. R. Hurley, K. Belczynski, M. Templeton, N. Ivanova, N. Ivanova, P. J. T. Leonard, P. Lu, P. Santolamazza, R. E. Cohen, R. Kippenhahn, S. Chatterjee, S. D. Kawaler, S. F. Portegies Zwart, S. J. Aarseth, S. Matt, S. Portegies Zwart, W. Benz, X. Chen, X. Chen, X. Chen   +44 more
core   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Desarrollo de un servicio en línea para la gestión tecnológica en salud

Revista Peruana de Medicina Experimental y Salud Pública
Objetivos. Desarrollar un servicio de asesoría en línea para la gestión tecnológica en salud, que contribuya a realizar procesos de evaluación y adquisición de equipos médicos según el mercado y las necesidades de las instituciones de salud. Materiales y
Victor Berrospi Polo, Juan Rodriguez Abad, Juan Bobadilla Aguilar, Carlos Di Liberto Moreno, Cecilia Díaz Arroyo, Carlos Rafael Quipan   +5 more
doaj   +2 more sources

Optimizing the ratio of captures to trapping effort in a black rat Rattus rattus control programme in New Zealand [PDF]

, 2013
The ratio of captures to unit effort is an important cost/benefit measure for volunteer pest control programmes. We describe an experiment designed to investigate the use of pre-feeding and trap pulsing as possible means of increasing this ratio.
King, Carolyn M., Scurr, Don
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Text-fading based training leads to transfer effects on children’s sentence reading fluency

Frontiers in Psychology, 2015
Previous studies used a text-fading procedure as a training tool with the goal to increase silent reading fluency (i.e., proficient reading rate and comprehension).
Telse eNagler, Telse eNagler, Sebastian Peter Korinth, Sebastian Peter Korinth, Janosch eLinkersdörfer, Janosch eLinkersdörfer, Jan eLonnemann, Jan eLonnemann, Björn eRump, Björn eRump, Marcus eHasselhorn, Marcus eHasselhorn, Marcus eHasselhorn, Sven eLindberg, Sven eLindberg   +14 more
doaj   +1 more source

Characteristic of Individual Indicators of Endogenous Intoxication in the Experimental Asthma Dynamics and Their Correction by Thiotriasolin [PDF]

, 2016
The aim of this work was to find out the specifics of changes in endogenous intoxication, middle mass molecules (MMM) and erythrocyte intoxication index (EII) in the blood of animals for experimental asthma in different periods of its development and to ...
Kolishetska, M. (Marta)
core   +2 more sources

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Why the Individual Mandate Matters [PDF]

, 2010
Compares estimates of coverage rates for the nonelderly and of spending by government, employers, individuals, and the overall health system under the 2010 healthcare reform law and estimates under a scenario in which the individual mandate is ...
Bowen Garrett, John Holahan, Matthew Buettgens   +2 more
core