Results 81 to 90 of about 18,856,199 (287)

Social sharing and expressive suppression in major depressive disorder and borderline personality disorder: An experience sampling study

Mental Health Science
Major depressive disorder (MDD) and borderline personality disorder (BPD) are characterized by disturbed patterns of emotional and interpersonal functioning, which might imply altered use of emotion regulation in interpersonal contexts.
Martine W. F. T. Verhees, Eva Ceulemans, Laura Sels, Egon Dejonckheere, Marlies Houben, Peter Kuppens   +5 more
doaj   +1 more source

Individual Fairness in Hindsight

, 2019
Since many critical decisions impacting human lives are increasingly being made by algorithms, it is important to ensure that the treatment of individuals under such algorithms is demonstrably fair under reasonable notions of fairness.
Gupta, Swati, Kamble, Vijay
core  

Individual emergence in contextual analysis [PDF]

, 2007
Located within the tradition of Hermeneutic Dialectics (HD) this paper offers an approach which can further an analysis of a fit between information and organizational systems.
Bednar, Peter
core  

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

Spatial representations of numbers and letters in children

Frontiers in Psychology, 2013
Different lines of evidence suggest that children’s mental representations of numbers are spatially organized in form of a mental number line. It is, however, still unclear whether a spatial organization is specific for the numerical domain or also ...
Jan eLonnemann, Jan eLonnemann, Janosch eLinkersdörfer, Janosch eLinkersdörfer, Telse eNagler, Telse eNagler, Marcus eHasselhorn, Marcus eHasselhorn, Marcus eHasselhorn, Sven eLindberg, Sven eLindberg   +10 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Warning signals for mental health problems in at‐risk young adults may be informed by momentary emotions reported by the general population: A novel application of the principles of statistical process control

Mental Health Science
Statistical process control (SPC) was recently introduced as a method for detecting person‐specific warning signals for mental ill‐health. Such warning signals occur when a person's repeatedly assessed emotions exceed a control limit.
Marieke J. Schreuder, Peter Kuppens, Evelien Schat, Peter deJonge, Catharina A. Hartman, Eva Ceulemans   +5 more
doaj   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

The Mediating Role of Self-Efficacy Perceptions in the Relationship Between Psychological Resilience and Health Anxiety of Special Education Teachers [PDF]

Balneo and PRM Research Journal
The purpose of this study is to examine the mediating role of self-efficacy perceptions in the relationship between psychological resilience levels and health anxiety among special education teachers.
Yunus Sahinler, Mustafa Can Koc, Busra Ozcan , Laurentiu-Gabriel Talaghir, Daniel Madalin Coja, Rodica Marinescu , Dan Eugen Costin , Chiung-Tzu Lucetta Tsai   +7 more
doaj   +1 more source