Machine Learning Models for the Prediction of Preterm Birth at Mid-Gestation Using Individual Characteristics and Biophysical Markers: A Cohort Study. [PDF]
Siargkas A +5 more
europepmc +1 more source
Gait speed and individual characteristics are related to specific gait metrics in neurotypical adults. [PDF]
Bonilla Yanez M +4 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Matrix Linear Models for Connecting Metabolite Composition to Individual Characteristics. [PDF]
Farage G +6 more
europepmc +1 more source
Analysis of individual characteristics influencing user polarization in COVID-19 vaccine hesitancy. [PDF]
Xie L, Wang D, Ma F.
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Personal Views of Aging Among Informal Caregivers of People with Dementia and Non-Caregivers: Gauging the Role of Individual Characteristics and Caregiving-Related Burden. [PDF]
Carbone E +9 more
europepmc +1 more source
Effects of Psychotherapy on the Problem Behaviors of Humidifier Disinfectant Survivors: The Role of Individual Characteristics and Adaptive Functioning. [PDF]
Lee MJ +5 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source

