Results 151 to 160 of about 18,428,291 (291)

Gait speed and individual characteristics are related to specific gait metrics in neurotypical adults. [PDF]

open access: yesSci Rep, 2023
Bonilla Yanez M   +4 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Matrix Linear Models for Connecting Metabolite Composition to Individual Characteristics. [PDF]

open access: yesMetabolites
Farage G   +6 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Personal Views of Aging Among Informal Caregivers of People with Dementia and Non-Caregivers: Gauging the Role of Individual Characteristics and Caregiving-Related Burden. [PDF]

open access: yesHealthcare (Basel)
Carbone E   +9 more
europepmc   +1 more source

Exploring Differences in Financial Literacy Across Countries: The Role of Individual Characteristics and Institutions

open access: yesSocial Indicators Research, 2018
Andrej Cupák   +3 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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