Results 131 to 140 of about 4,871,172 (231)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Amur Tiger Individual Identification Based on the Improved InceptionResNetV2. [PDF]

Animals (Basel)
Wu L, Jinma Y, Wang X, Yang F, Xu F, Cui X, Sun Q.   +6 more
europepmc   +1 more source

The impact of anthropogenic noise on individual identification via female song in Black-capped chickadees (Poecile atricapillus). [PDF]

Sci Rep, 2021
Montenegro C, Service WD, Scully EN, Mischler SK, Sahu PK, Benowicz TJ, Fox KVR, Sturdy CB.   +7 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Evaluation of mtDNA analysis as a screening method prior to individual identification by short tandem repeat analysis of sika deer (<i>Cervus nippon</i>) for illegal disposal of hunting in Japan. [PDF]

Front Vet Sci
Tanaka A, Ueda R, Udagawa C, Omi T, Kihara Y, Hayama SI.   +5 more
europepmc   +1 more source

Genetic diversity analysis of forty-three insertion/deletion loci for forensic individual identification in Han Chinese from Beijing based on a novel panel. [PDF]

J Zhejiang Univ Sci B, 2022
Zhao C, Yang J, Xu H, Mei S, Fang Y, Lan Q, Deng Y, Zhu B.   +7 more
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Individual identification of sika deer (Cervus nippon) using short tandem repeat analysis for investigating illegal carcass disposal in Japan. [PDF]

PLoS One
Tanaka A, Ueda R, Udagawa C, Omi T, Kihara Y, Hayama SI.   +5 more
europepmc   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Genetic insights for enhancing conservation strategies in captive and wild Asian elephants through improved non-invasive DNA-based individual identification. [PDF]

PLoS One
Quainoo DK, Chalermwong P, Muangsuk P, Nguyen THD, Panthum T, Singchat W, Budi T, Duengkae P, Suksavate W, Chaiyes A, Sanannu S, Tipkantha W, Bangkaew N, Sripiboon S, Muangmai N, Han K, Maneeorn P, Kaewparuehaschai M, Leamsaard G, Kanchanasaka C, Srikulnath K.   +20 more
europepmc   +1 more source