Results 191 to 200 of about 4,871,172 (231)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Oral mark in the application of an individual identification: From ashes to truth.

J Forensic Dent Sci, 2017
Chugh A, Narwal A.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Checkwriter Identification—Individuality

Journal of Forensic Sciences, 1982
Abstract Checkwriters are established machines in the contemporary business world and, as such, are an established vehicle of criminal action. This paper offers practical suggestions for the identification of checkwriters through their impressions from information gained through original research.
TW Vastrick, EJ Smith
openaire   +1 more source

NATIONAL INDIVIDUAL IDENTIFICATION OF HORSES

Australian Veterinary Journal, 1977
Methods of equine identification including signalment, blood typlng, tattooing and freeze marking are discussed. A new system of individually identifying horses with an unalterable freeze mark is proposed. Unalterable numerical and alphabetical symbols have been developed to apply a registration number to the animal.
R K, Farrell, B J, Hilbert
openaire   +2 more sources

ECG to Individual Identification

2008 IEEE Second International Conference on Biometrics: Theory, Applications and Systems, 2008
This paper presents an individual identification system using single lead electrocardiogram (ECG). The proposed techniques for P and T wave delineation are based on time derivative and adaptive thresholding. The performance of proposed delineators is evaluated on manually annotated Physionet QT database.
Yogendra Narain Singh, Phalguni Gupta
openaire   +1 more source

SNPs for individual identification

Forensic Science International: Genetics Supplement Series, 2008
Abstract Using population genetics criteria for SNPs for individual identification (IISNPs) – SNPs having nearly maximum informativeness in populations from all parts of the world – on a reduced screening panel of 31 populations, those most likely to be forensically relevant, we have identified a panel of 108 candidate SNPs that meet our ...
A.J. Pakstis, W.C. Speed, J.R. Kidd, K.K. Kidd   +3 more
openaire   +1 more source

Molecular Identification of Individual Nano-Objects

Analytical Chemistry, 2009
Secondary ion mass spectrometry (SIMS) run in the event-by-event bombardment/detection mode provides a unique ability to obtain molecular information from single nano-objects, since assays are based on secondary ion coemission from single impacts. The characterization of individual nano-objects is demonstrated with negatively charged polymer spheres ...
Veronica T, Pinnick, Stanislav V, Verkhoturov, Leonid, Kaledin, Yordanos, Bisrat, Emile A, Schweikert   +4 more
openaire   +2 more sources