Results 31 to 40 of about 533,821 (259)

A cross-cohort replicable and heritable latent dimension linking behaviour to multi-featured brain structure

open access: yesCommunications Biology, 2022
Multivariate brain-behaviour associations are studied with regularized canonical correlation analysis and a machine learning framework, showing that behavioural inter-individual variability is linked to inter-individual variability in brain structure.
Eliana Nicolaisen-Sobesky   +11 more
doaj   +1 more source

Individual Claims History Simulation Machine [PDF]

open access: yesSSRN Electronic Journal, 2018
The aim of this project is to develop a stochastic simulation machine that generates individual claims histories of non-life insurance claims. This simulation machine is based on neural networks to incorporate individual claims feature information. We provide a fully calibrated stochastic scenario generator that is based on real non-life insurance data.
Andrea Gabrielli, Mario V. Wuthrich
openaire   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Ensemble learning based functional independence ability estimator for pediatric brain tumor survivors

open access: yesHealth Informatics Journal, 2022
A history of brain tumor strongly affects children’s cognitive abilities, performance of daily activities, quality of life, and functional outcomes.
Pei-Hua Lin, Ping-Huan Kuo
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

The optimal crowd learning machine

open access: yesBioData Mining, 2017
Background Any family of learning machines can be combined into a single learning machine using various methods with myriad degrees of usefulness. Results For making predictions on an outcome, it is provably at least as good as the best machine in the ...
Bilguunzaya Battogtokh   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Examining Individual Tax Morale in Europe with Machine-Learning Methods

open access: yesCentral European Public Administration Review
Purpose: This research examines and contributes to the behavioural lit­erature on voluntary tax compliance. It focuses on the use and potential of machine-learning (ML) methods and models to predict individual tax morale across Europe, and it identifies
Lejla Lazović Pita   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Home - About - Disclaimer - Privacy