Results 61 to 70 of about 2,368,157 (325)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
IEEE Access, 2021 Power system transient stability assessment (TSA) and control is a complex problem. TSA from the perspective of individual machine Kimbark curves forms a distinctive approach. On the other hand, transient stability constrained optimal power flow (TSC-OPF)
Sreenadh Batchu, Kiran Teeparthi
doaj +1 more source
Individual Explanations in Machine Learning Models: A Survey for Practitioners
CoRR, 2021 In recent years, the use of sophisticated statistical models that influence decisions in domains of high societal relevance is on the rise. Although these models can often bring substantial improvements in the accuracy and efficiency of organizations, many governments, institutions, and companies are reluctant to their adoption as their output is often
Alfredo Carrillo +2 more
openaire +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Communications, 2020 General mobility estimation is demanded for strategy, policy, systems and services developments and operations in transport, urban development and telecommunications.
Renato Filjar +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Does machine learning outperform logistic regression in predicting individual tree mortality?
Ecological InformaticsTree mortality is a crucial process in forest dynamics and a key component of forest growth models and simulators. Factors like competition, drought, and pathogens drive tree mortality, but the underlying mechanism is challenging to model.
Aitor Vázquez-Veloso +5 more
doaj +1 more source
Cyber equipping 4.0 – fe-simulation-based setting instructions for a rotary draw-bending machine [PDF]
, 2017 The tool setting process for rotary draw-bending is very complex. Only experienced machine operators know which settings lead to a good result in relation to the bending task.
Abele, Darwin +7 more
core
To Study variations in Blood Pressure (BP) Recording by Mercurial Sphygmomanometer & by LED (Non-Mercurial) BP Machine in Individuals in Sitting Position in Same Arm - A Cross Sectional Study in Guwahati City [PDF]
, 2021 Arijit Mazumdar, Reeta Baishya
openalex +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source