Results 1 to 10 of about 205,197 (219)

Bacterial Signatures of Paediatric Respiratory Disease: An Individual Participant Data Meta-Analysis [PDF]

open access: yesFrontiers in Microbiology, 2021
Introduction: The airway microbiota has been linked to specific paediatric respiratory diseases, but studies are often small. It remains unclear whether particular bacteria are associated with a given disease, or if a more general, non-specific ...
David T. J. Broderick   +49 more
doaj   +7 more sources

Quantifying heterogeneity in individual participant data meta-analysis with binary outcomes [PDF]

open access: yesSystematic Reviews, 2017
Background In meta-analyses (MA), effect estimates that are pooled together will often be heterogeneous. Determining how substantial heterogeneity is is an important aspect of MA.
Bo Chen, Andrea Benedetti
doaj   +3 more sources

Post-traumatic stress disorder, trauma and parenting stress: an individual participant data meta-analysis [PDF]

open access: yesEuropean Journal of Psychotraumatology
Background: Parental post-traumatic stress disorder (PTSD) symptoms are associated with heightened parenting stress, but it is unknown whether this relation depends on the timing (childhood or adulthood) and type of trauma (interpersonal or non ...
Laurien Meijer   +20 more
doaj   +2 more sources

Increased risk of death following release from incarceration: an individual participant data meta-analysis of 1,314,568 adults in eight countries.

open access: yesInternational Journal of Population Data Science, 2022
Objectives People released from incarceration are at increased risk of death from diverse causes. We aimed to calculate the incidence of all-cause and cause-specific death after release from incarceration and identify individual-level risk factors for ...
Rohan Borschmann   +3 more
doaj   +1 more source

Overlapping research efforts in a global pandemic: a rapid systematic review of COVID-19-related individual participant data meta-analyses

open access: yesBMC Health Services Research, 2023
Background Individual participant data meta-analyses (IPD-MAs), which involve harmonising and analysing participant-level data from related studies, provide several advantages over aggregate data meta-analyses, which pool study-level findings.
Lauren Maxwell   +5 more
doaj   +1 more source

Ethnic differences in response to atypical antipsychotics in patients with schizophrenia: individual patient data meta-analysis of randomised placebo-controlled registration trials submitted to the Dutch Medicines Evaluation Board

open access: yesBJPsych Open, 2023
Background Little is known about the effect of ethnicity on the response to antipsychotic medication in patients with schizophrenia. Aims To determine whether ethnicity moderates the response to antipsychotic medication in patients with schizophrenia ...
Bram W. C. Storosum   +8 more
doaj   +1 more source

Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies

open access: yesFrontiers in Psychiatry, 2022
BackgroundIn non-randomized studies (NRSs) where a continuous outcome variable (e.g., depressive symptoms) is assessed at baseline and follow-up, it is common to observe imbalance of the baseline values between the treatment/exposure group and control ...
Lamprini Syrogiannouli   +36 more
doaj   +1 more source

Association between cannabis use and symptom dimensions in schizophrenia spectrum disorders: an individual participant data meta-analysis on 3053 individualsResearch in context

open access: yesEClinicalMedicine, 2023
Summary: Background: The association between cannabis use and positive symptoms in schizophrenia spectrum disorders is well documented, especially via meta-analyses. Yet, findings are inconsistent regarding negative symptoms, while other dimensions such
Mathilde Argote   +36 more
doaj   +1 more source

Optimism in adults born preterm: Systematic review and individual-participant-data meta-analysis

open access: yesPLoS ONE, 2021
Aim Preterm birth(
Rachel K. Robinson   +11 more
doaj   +3 more sources

Methotrexate vs expectant management for treatment of tubal ectopic pregnancy: An individual participant data meta‐analysis

open access: yesActa Obstetricia et Gynecologica Scandinavica, 2023
Introduction Ectopic pregnancy is an important health condition which affects up to 1 in 100 women. Women who present with mild symptoms and low serum human chorionic gonadotrophin (hCG) are often treated with methotrexate (MTX), but expectant management
Sarah Annie Solangon   +5 more
doaj   +1 more source

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