Results 91 to 100 of about 43,105,901 (290)

Primary esophageal lymphoma: An individual participant data meta-analysis

Surgery
Primary esophageal lymphoma represents a rare form of gastrointestinal lymphoma, comprising less than 1% of all lymphomas. This study aims to review the literature on primary esophageal lymphoma, examining its clinical features, diagnosis, treatment, prognosis, and biological behavior.A systematic search of the literature in the PubMed/Medline and ...
Adam Mylonakis, Maria Dimitrakoudi, Diamantina Vasilatou, Dimitrios Tsapralis, Georgios Vasiliadis, Nikolaos Koliakos, Panagiotis Sakarellos, Emmanouil I. Kapetanakis, Dimitrios Schizas   +8 more
openaire   +2 more sources

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Using individual participant data to improve network meta-analysis projects.

, 2023
A network meta-analysis combines the evidence from existing randomised trials about the comparative efficacy of multiple treatments. It allows direct and indirect evidence about each comparison to be included in the same analysis, and provides a coherent
Dias, Sofia, Donegan, Sarah, Efthimiou, Orestis, Phillippo, David M, Tierney, Jayne F, Stewart, Lesley A, Riley, Richard D   +6 more
core   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

A case study of an individual participant data meta-analysis of diagnostic accuracy showed that prediction regions represented heterogeneity well

, 2023
A case study of an individual participant data meta-analysis of diagnostic accuracy showed that prediction regions represented heterogeneity ...
HR Baradaran (14468328), MH Chagas (14468337), D Fung (7774805), S Mohd Sidik (13397943), P Persoons (13397961), K Reuter (10320608), K Muramatsu (13397949), ALMV de Lara (16449279), U Hegerl (13397886), M Härter (13397883), B Löwe (13397928), J Shaaban (13397982), SB Patten (14449281), JM de Man-van Ginkel (14468343), K Ismail (10029893), FL Osório (14468364), V Patel (7804106), Y Wu (808222), J Boruff (13397814), DH Akena (14468322), Y Conwell (13421082), KE Riehm (11560279), J Delgadillo (13421088), A Picardi (13397964), J White (7674893), M Inagaki (13397898), BJ Hall (15856814), CH Bombardier (14468334), SR Loureiro (14468358), Peter Butterworth (14681629), L Hides (13290525), Y Zhang (5998940), M Hudson (13397895), PM Bhandari (14449269), B Gelaye (13397868), CG Greeno (15856811), AG Rooney (14449326), CM van der Feltz-Cornelis (14423802), PA Vöhringer (14468382), N Saadat (13421034), P Cuijpers (13381317), SI Liu (14468355), L Marsh (4983266), KM Kiely (14757418), T Hyphantis (13303365), A Beraldi (13397829), K Winkley (13421157), SE Hobfoll (15834650), A Simning (13512400), F Goodyear-Smith (8862596), LA Kloda (14449296), IS Santos (7723055), G Carter (11066991), F Lamers (65219), A Sidebottom (13511200), JCN Chan (7771157), DB Rice (14449272), B Arroll (7796105), ME Khamseh (14468352), L Ayalon (13397823), D McMillan (13332153), PLL Tan (15856829), Z Negeri (13397799), M Yamada (8024867), A Benedetti (13397790), BW Pence (14468370), SC Sung (14468376), N Jetté (13397904), N Chowdhary (13512388), JR Fann (14468346), FH Fischer (14449311), L Stafford (13397991), HC van Weert (15856832), A McGuire (13511197), C He (7754612), Alyna Turner (13057884), I Shrier (11170659), R Cholera (13421076), M Lotrakul (13397922), Y Sun (3556880), A Krishnan (13334199), D Neupane (7785593), B Levis (13397781), MA Whooley (14468385), M Azar (13397808), Y Kwan (13397910), TN Munhoz (15856880), S Gilbody (13207859), JPA Ioannidis (7675757), B Thombs (16449282), K Clover (13421079), RC Ziegelstein (14449284), M Imran (12678580)   +92 more
core   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Meta-Analysis within a Single Paper Using Individual-Participant Data: A Simpler Alternative

, 2022
More researchers recognize the importance of meta-analyzing findings within a single paper (i.e., mini meta-analysis). These analyses have been primarily conducted by meta-analyzing aggregated data at the study level, particularly the effect size of each
Wong, Ellick Kin Fai, Kwong, Jessica Y. Y.   +1 more
core   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Supplemental Material - Correlations between comorbidities in trials and the community: An individual-level participant data meta-analysis

, 2023
Supplemental Material for Correlations between comorbidities in trials and the community: An individual-level participant data meta-analysis by Jamie Crowther, Elaine W Butterly, Laurie J Hannigan, Bruce Guthrie, Sarah H Wild, Frances S Mair, Peter ...
Jamie Crowther (17067814), Bruce Guthrie (434189), Fergus J Chadwick (17371979), David A McAllister (12790079), Elaine W Butterly (17371973), Frances S Mair (5195426), Laurie J Hannigan (17371976), Peter Hanlon (3498404), Sarah H Wild (8950793)   +8 more
core   +1 more source