Results 241 to 250 of about 43,105,901 (290)
Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC
Advanced Science, EarlyView.Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.Ning Zhang, Tong Wan, Siyue Zhang, Yunzhen Jiang, Peng Su, Jixin Liu, Zhitong Chen, Jie Hao, Haoyu Wang, Bing Chen, Wenjing Zhao, Lijuan Wang, Tao Xing, Qihuang Zhang, Ulf Schmitz, Zhiyong Ding, Nicola Crosetto, Bingqiang Liu, Qifeng Yang +18 morewiley +1 more sourceMachine Learning-Based Sleep Electroencephalographic Brain Age Index and Dementia Risk: An Individual Participant Data Meta-Analysis.
JAMA Netw OpenSun H, Milton S, Fang Y, Taha HB, Shiju S, Thomas RJ, Ganglberger W, Pase MP, Hughes T, Purcell S, Redline S, Stone KL, Yaffe K, Westover MB, Leng Y. +14 moreeuropepmc +1 more sourceBioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism
Advanced Science, EarlyView.Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li +7 morewiley +1 more sourceExamining the factor structure of the 40-item Defense Style Questionnaire among adults with depression: an individual participant data meta-analysis. [PDF]
Res PsychotherWienicke FJ, Burk WJ, Heinonen E, Lindfors O, Härkänen T, Knekt P, Sarvasmaa S, Dias de Mattos Souza L, Jansen K, Azevedo da Silva R, Nobre Dos Santos É, Dekker JJM, Peen J, Van HL, Perry JC, Van der Veld WM, Soares E, Spijker J, Driessen E. +18 moreeuropepmc +1 more sourceIntravenous thrombolysis for acute central retinal artery occlusion: Protocol for a systematic review and individual participant data meta-analysis of randomized controlled trials. [PDF]
PLoS OneMac Grory B, Preterre C, Lebranchu P, Ryan SJ, Kalsnes Jørstad Ø, Moe MC, Tünnerhoff J, Spitzer MS, Grohmann C, Dumitrascu OM, Biousse V, Guillon B, Aamodt AH, Poli S, Schrag M, Central Retinal ArterY OcclusioN (CRAYON) Collaborators. +15 moreeuropepmc +1 more sourceTranscatheter or Surgical Treatment of Patients With Aortic Stenosis at Low to Intermediate Risk: An Individual Participant Data Meta-Analysis.
JAMA CardiolLudwig S, Klimek M, Bay B, Blankenberg S, Granada JF, Hildick-Smith D, Hudson J, Jørgensen TH, Leon MB, Magnussen C, Thiele H, Hørsted Thyregod HG, Wendler O, de Backer O, Toff WD, Ziegler A, Seiffert M. +16 moreeuropepmc +1 more sourceEffective Components of Collaborative Care for Depression in Primary Care: An Individual Participant Data Meta-Analysis.
JAMA PsychiatrySchillok H, Gensichen J, Panagioti M, Gunn J, Junker L, Lukaschek K, Jung-Sievers C, Sterner P, Kaupe L, Dreischulte T, Ali MK, Aragonès E, Bekelman DB, Herbeck Belnap B, Carney RM, Chwastiak LA, Coventry PA, Davidson KW, Ekstrand ML, Flehr A, Fletcher S, Hölzel LP, Huijbregts K, Mohan V, Patel V, Richards DA, Rollman BL, Salisbury C, Simon GE, Srinivasan K, Unützer J, van der Feltz-Cornelis CM, Wells KB, Zimmermann T, Bühner M, POKAL Group. +35 moreeuropepmc +1 more source