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Individual Participant Data (IPD) Meta-Analysis
2021Individual participant data (IPD) meta-analyses are relatively new compared with the traditional aggregate data meta-analyses. IPD meta-analyses involve the collection, checking, and re-analysis of the original data for each participant in each study.
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An individual participant data meta-analysis
2021Objective: Behavioral interventions are well established treatments for children with attention-deficit/hyperactivity disorder (ADHD). However, insight into moderators of treatment outcome is limited. Method: We conducted an individual participant data meta-analysis (IPDMA), including data of randomized controlled behavioral intervention trials for ...
Groenman, Annabeth P. +33 more
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Retrieval barriers in individual participant data reviews with network meta-analysis
BMJ Evidence-Based Medicine, 2022ObjectivesIndividual participant data (IPD) from randomised controlled trials (RCTs) can be used in network meta-analysis (NMA) to underpin patient care and are the best analyses to support the development of guidelines about the use of healthcare interventions for a specific condition. However, barriers to IPD retrieval pose a major threat. The aim of
Areti Angeliki Veroniki +5 more
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Empathic disequilibrium in schizophrenia: An individual participant data meta-analysis
Journal of Psychiatric ResearchSchizophrenia involves substantial social difficulties, yet their nature remains unclear. Although empathy has been considered a promising social cognition construct, inconsistent findings have undermined its usefulness as a stable index for schizophrenia.
Ido Shalev +6 more
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Including Individual Participant Data in Meta-analysis
2011This chapter introduces methods for including individual participant data in a traditional meta-analysis. Since meta-analyses use data aggregated to the study, there is potential for aggregation bias, finding relationships between the effect size and study characteristics that may hold only at the level of the study.
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Individual participant data meta-analysis of prognosis studies
2019An alternative approach to meta-analysis of aggregate data from published prognosis research (as addressed in Chapter 9), with its challenges of heterogeneity and lack of information, is to conduct meta-analysis of individual participant data (IPD), that is, the original raw data of the individuals who are included in the primary prognosis studies. The
Richard D Riley +2 more
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Combining individual participant and aggregated data in a meta‐analysis with correlational studies
Research Synthesis Methods, 2012This paper presents methods for combining individual participant data (IPD) with aggregated study level data (AD) in a meta‐analysis of correlational studies. Although medical researchers have employed IPD in a wide range of studies, only a single example exists in the social sciences.
Terri, Pigott +2 more
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Efficacy of isoniazid in paediatric tuberculosis: an individual participant data meta-analysis
European Respiratory JournalBackground Isoniazid is a cornerstone of management therapy for tuberculosis (TB). Our aim was to determine the association between isoniazid exposure and clinical outcomes, to develop a pharmacokinetic model, and to optimise the dosing regimen in children treated for drug-susceptible (DS)-TB.
Agathe Béranger +28 more
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