Results 111 to 120 of about 7,148,171 (303)

Resilient individuals: sexual orientation, gender identity and intersex rights 2015

open access: yes, 2015
The status of SOGII rights in Australia has improved significantly over the past two decades. Despite this, LGBTI people still face unacceptable and significant discrimination and barriers to their fair and equal treatment, according to this report ...
Australian Human Rights Commission
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

The Court of Justice of the European Union as a fundamental rights tribunal: challenges for the effective delivery of fundamental rights in the area of freedom, security and justice. CEPS Paper in Liberty and Security in Europe No. 49, 29 August 2012 [PDF]

open access: yes, 2012
This paper reflects on the challenges facing the effective implementation of the new EU fundamental rights architecture that emerged from the Lisbon Treaty. Particular attention is paid to the role of the Court of Justice of the European Union (CJEU) and
Petkova, Bilyana   +2 more
core  

Judicialization of Health Policy in the Definition of Access to Public Goods: Individual Rights versus Collective Rights

open access: yesBrazilian Political Science Review, 2010
The article analyses a form of judicialization of public policies in the health field. It has as its object lawsuits initiated against Belo Horizonte Municipality arguing for the provision of services or the acquisition of inputs not obtained in the ...
Telma Maria Gonçalves Menicucci   +1 more
doaj  

THE INDIVIDUAL RIGHTS AND THE STATE [PDF]

open access: yesChallenges of the Knowledge Society, 2011
The concept of man’s individual rights appeared a long time ago as a means of the individual’s protection in relationship with the others. Living in a society, man interacts with other people, and these relations are regulated by certain rules.
DANA TITA, CEZAR TITA
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

A meaningful Human Rights Council in 2030: Catalyse National Rights Protection

open access: yes, 2016
Rather than celebrating the 10th anniversary of the UN Human Rights Council, we should take a moment to reflect upon what must be improved. This applies not only to States but also to civil society.
Kletzel, Gabriela   +3 more
core  

Reconstructing Individual Rights and Social Obligations in Islamic Family Law

open access: yesMazahibuna: Jurnal Perbandingan Mazhab
Contemporary Islamic family law faces growing tensions between the protection of individual rights and the preservation of social obligations amid the expansion of liberal individualism and changing family structures.
Yusri Muhammad Arsyad   +3 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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