Results 101 to 110 of about 7,148,171 (303)

Other title: Employment Law's Clark Kent; Other title: ow You Can be a Superhero, Too!

open access: yes, 2017
"7/7/2017."Kansas Human Rights Commission -- Harassment: Demonstrating "Reasonable Care" -- The Complaint Process -- The Investigation -- Disability: Engaging in the Interactive ...
Kansas Human Rights Commission.
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Immediate Release, August 17, 2012

open access: yes, 2012
"August 17, 2012.""The Kansas Human Rights Commission (KHRC) is pleased to announce that Robert G. Lay, formerly of Topeka, Kansas, and Rehelio "Ray" A.
Kansas Human Rights Commission.
core  

Majority Rule and Individual Rights: Can Rousseau’s General Will Foster Genuine Democracy in Nigeria?

open access: yesActa Universitatis Danubius: Administratio
This study examines the tension between majority rule and individual rights in Nigeria’s democratic experience, drawing on Jean-Jacques Rousseau’s concept of the “General Will.” While democracy is premised on majority decision-making, unchecked ...
Asimiyu Olalekan Murana   +1 more
doaj  

ProtectingIndividual Rights: Analyzing ICJ Judgment in the Case of Guinea Against Congo [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2015
International court of justice as main judicial organ of United Nations not only has duty to resolve disputes between states but also has duty for protecting values which are accepted by members of international community. However, it has duty to resolve
Mohsen Abdollahi, Ali Hasankhani
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transferable Rights of Recreational Fishery: An Application to Red Snapper Fishery in the Gulf of Mexico [PDF]

open access: yes
Transferable rights (TRs) programs are being increasingly considered in fisheries to overcome current overfishing situation. This paper will focus on developing a conceptual foundation, investigating advantages of the TRs program in fishery management ...
Kim, Hwa Nyeon   +2 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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