Results 81 to 90 of about 6,447 (214)
The History and Practice of Substantive Due Process: A Question of Legitimacy
Trento Student Law Review, 2019 While the concept of substantive due process can be found in judicial decision-making prior to the Civil War, in the 1960s it became and has remained a lightning rod among the juristic community.
James Marmaduke
doaj
Negative and Positive Freedom: The Case of Turkey
Review of European and Comparative LawThe meaning of the concept of freedom has constantly changed in history. In Ancient Greece, freedom referred to making a choice and doing something willingly; Hannah Arendt conceptualized it as a necessary discovery made by people in historical periods ...
Tacettin Gökhan Özçelik
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
On Limited Communitarianism: Matolino’s Thinking and the Changing African World
ArụmarụkaIn the corpus of African philosophy, Bernard Matolino has made a substantial contribution to the development of communitarian theory, offering a fresh perspective on the concept.
Mutshidzi MARAGANEDZHA
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THE INDIVIDUAL RIGHTS AND THE STATE [PDF]
Challenges of the Knowledge Society, 2011 The concept of man’s individual rights appeared a long time ago as a means of the individual’s protection in relationship with the others. Living in a society, man interacts with other people, and these relations are regulated by certain rules.
DANA TITA, CEZAR TITA
doaj
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source