Results 111 to 120 of about 63,434 (255)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
In St. Maximus the Confessor’s teaching human nature consists of the soul and the body, in which logos of power that unifies them together is inscribed. Human nature manifests itself in the individual human being. The human being as the body and the soul
Kashchuk, Oleksandr
core
Jack Worthing’s Pursuit Of Love Reflected In Oscar Wilde’s The Importance Of Being Earnest Play : An Individual Psychological Approach [PDF]
This study is about Pursuit of Love. The problem of this study is to reveal how the pursuit of love in major character named Jack Worthing is pursuing his love reflected in The Importance of Being Earnest play created by Oscar Wilde.
Saputra, Adhityas Surya +2 more
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The Myth of Urban Unity. Religion and Social Performance in Late Medieval Braunschweig
Arlinghaus F-J. The Myth of Urban Unity. Religion and Social Performance in Late Medieval Braunschweig. In: Goodson C, Lester AE, Symes C, eds. Cities, Texts, and Social Networks, 400-1500: Experiences and Perceptions of Medieval Urban Space.
Goodson, Caroline +3 more
core
Research framework: Given the setting of weak institutional unity for the elderly, intergenerational family ties are now, more than ever, being challenged by a rapidly ageing population. Men and women are living longer lives that are marked by dependence.
Sadio Ba Gning
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Life satisfaction, household income and personality traits [PDF]
We show that personality traits mediate the effect of income on Life Satisfaction. The effect is strong in the case of Neuroticism, which measures the sensitivity to threat and punishment, in both the British Household Panel Survey and the German ...
Rustichini, Aldo, Proto, Eugenio
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source

