Results 121 to 130 of about 63,434 (255)

Beyond the Individual-Society Dualism. Georg Simmel's Lesson

open access: yes, 2016
Simmel’s lesson highlights some possible weaknesses of the anthropological vision that supports the modern and, in some ways, also the post-modern socio-economic model: the individual-society dualism.
Martinelli, Monica
core  

Seniors sentiment index [PDF]

open access: yes, 2012
The ageing of the Australian population presents numerous opportunities and it is important to understand how senior Australians view different aspects of their own lives, as well as life in Australia more generally.  A summary index is a valuable ...

core  

Zygotes, Souls, Substances, and Persons

open access: yes, 1990
The thesis that the human zygote is essentially identical with the person into which it can develop is difficult to maintain, because the zygote can become several persons.
Bole, Thomas J.
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Happiness as a Driver of Risk-Avoiding Behavior [PDF]

open access: yes
Most governments try to discourage their citizens from taking extreme risks with their health and lives. Yet, for reasons not understood, many people continue to do so. We suggest a new approach to this longstanding question. First, we show that expected-
Jan-Emmanuel De Neve   +4 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Social History and Private Life Story in the Play by L. Petrushevskaya “Moscow Choir” (“Moskovskiy khor”)

open access: yesФилологический класс, 2011
The article explores interdependence of ethical awareness of the characters and social-historical reality. The author proves the impossibility of harmonizing the history and the being of an individual by analyzing the problems, the subject-matter, and ...
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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