Results 71 to 80 of about 368,296 (265)

Diagnosis of Leadership Potential in High School Students with Special Needs in the Environment of an Inclusive Educational Institution

Konteksty Pedagogiczne, 2019
There is a need in Ukraine to create special conditions in higher educational institutions to serve the increasing number of people with special needs.
Olga Soroka, Svitlana Kalaur
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Lived experiences of a Tagasalo having siblings with special needs: An educational implication

Journal of Educational Management and Instruction
This study focuses on the lived experiences of individuals with siblings with special needs as their tagasalo. It is deeply rooted in Filipino culture and refers to an individual who selflessly takes on the role of a caregiver.
Lindy Chielo I. Pabatang, Janus A. Naparan   +1 more
doaj   +2 more sources

Using Animation as a Means of Enhancing Learning of Individuals with Special Needs

TEM Journal, 2018
Use of animation in special education has gained great attention recently. Therefore, the use of animation for helping individuals with special needs has become an important research question and this study aims to examine and discuss the role of using animation as a tool to enhance learning of individuals with special needs.
Bağlama, Başak, Yücesoy, Yücehan, Yıkmış, Ahmet   +2 more
openaire   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Nutrition for Individuals with Special Needs: Advocacy Guide

Special needs is a broad term that includes numerous conditions, such as children born with congenital conditions such as cerebral palsy, to a woman with chronic arthritis, to elderly individuals dealing with dementia, to anyone who lost one or more of their motor limbs in an accident or war.
Ayoub Al-Jawaldeh, Mandy Taktouk, Alaa Al-Bakheit, Amina Barkat, Hanin Al-Jawaldeh, Hazem Agha, Reema Tayyem   +6 more
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Prevocational training situation of young people with special educational needs (SEN) in Germany

Social Welfare: Interdisciplinary Approach, 2012
The article presents the analysis of educational situation of young people with Special Educational Needs (SEN) in Germany based on the example of Prevocational Training in a Vocational Training Institute.
Ursula Spichtinger, Aistė Valaikienė
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source