Results 151 to 160 of about 101,556 (381)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Yesus Kristus sebagai Arketipe Gereja: Menuju Gereja yang Terbuka Terhadap LGBT

Gema Teologika
This paper challenges the church’s exclusion of LGBT individuals, who have been deemed sinners and thus unworthy of participating in ecclesiastical communion.
Yosia Polando Ressa
doaj   +1 more source

Path to Wholeness: The Serpent-Haired Gorgon’s Individuation Journey in Jessie Burton’s Retelling Medusa: The Girl Behind the Myth (2021) [PDF]

Mariam Fathy Omran
openalex   +1 more source

Conceptual Role Semantics, the Theory Theory, and Conceptual Change [PDF]

, 2004
The purpose of the paper is twofold. I first outline a philosophical theory of concepts based on conceptual role semantics. This approach is explicitly intended as a framework for the study and explanation of conceptual change in science. Then I point to
Brigandt, Ingo
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Sens et conditions des crises de la forme scolaire et de son évolution

Penser l'Éducation
The observation of a crisis of the school form predominates today in scholarly literature and opinion, but how to objectify it? For philosophy, such a diagnosis brings together questions at the same time axiological, epistemological and political, even ...
Emmanuel Brassat
doaj   +1 more source

A Long-Term Effect of Perceptual Individuation Training on Reducing Implicit Racial Bias in Preschool Children.

Child Development, 2019
Miao K. Qian, P. Quinn, Gail D. Heyman, O. Pascalis, Genyue Fu, Kang Lee   +5 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The identity of what? Pluralism, practical interests, and individuation [PDF]

Vilius Dranseika, Shaun Nichols, D. H. Shoemaker   +2 more
openalex   +1 more source