Results 131 to 140 of about 98,593 (351)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Who Is (Not) Individual: Individualism, Individuality, and Negation
, 2020 Relying on a scene from Monty Python's Life of Brian movie, the article would indicate the characteristically modern dilemmas in the understanding of the category of individual. The speech which Brian delivers to his assembled followers, and the reactions to it, amusingly display typical conceptual problems arising in both, the contemporary crucial and
openaire +1 more source
Function attribution depends on the explanatory context: A Reply to Neander and Rosenberg's Reply to Nanay [PDF]
, 2012 In ‘A modal theory of function’, I gave an argument against all existing theories of function and outlined a new theory. Karen Neander and Alex Rosenberg argue against both my negative and my positive claim.
Nanay, Bence
core
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Non compliance in organic certification: determinants for Italy [PDF]
, 2011 Organic certification is based on controls on operators, and verify if they are compliant with respect to organic regulations. Control procedures are a transaction cost that affect organic farming relative competiveness.
Gambelli, Danilo +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Individuation and Movements of Existence in Jan Patočka
Theology and Philosophy of EducationJan Patočka addresses the concept of individuation in relation to the three movements of existence. This article argues that education functions as a process of individuation, requiring educators to engage with the third movement of existence in order ...
Lina Marcela Gil-Congote
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Individual Home Advantage with Individual Data
, 2021 Home advantage (HA) is a well-documented phenomenon in (professional) team sports. However, there is also a growing body of evidence that in individual sports home athletes have an advantage. I define HA as ‘the performance advantage of an athlete, team, or country when they compete at a home ground compared to their performance under similar ...
openaire +2 more sources